For further investigations in IgA nephropathy the approach from phenotype to genotype is welcome

Clinical and Experimental Immunology

Volumn 127, Issue 3, 2002, Pages 399-401

  Schena, F P ^a,b  

^a UNIVERSITY OF BARI   (Italy)

^b POLICLINICO   (Italy)

Author keywords

Genome wide analysis; IgA nephropathy; Immunological abnormalities

Indexed keywords

B LYMPHOCYTE; CLINICAL FEATURE; CYTOKINE PRODUCTION; DISEASE COURSE; DNA MICROARRAY; DUODENUM MUCOSA; EDITORIAL; GENE EXPRESSION; GENOTYPE; HEREDITY; HUMAN; IMMUNE SYSTEM; IMMUNOGLOBULIN A NEPHROPATHY; IMMUNOGLOBULIN BLOOD LEVEL; KIDNEY DISEASE; MASS SPECTROMETRY; MOLECULAR GENETICS; PATHOGENESIS; PHENOTYPE; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; T LYMPHOCYTE;

GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; GLOMERULONEPHRITIS, IGA; HUMANS; IMMUNOGLOBULIN VARIABLE REGION; PHENOTYPE; POLYMORPHISM, GENETIC; RECEPTORS, ANTIGEN, T-CELL, GAMMA-DELTA; T-LYMPHOCYTES;

EID: 0036237470     PISSN: 00099104     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2249.2002.01821.x     Document Type: Editorial

References (15)

1. Expression of T cell receptor variable region families by bone marrow γδ T cells in patients with Iga Nephropathy
2. Expression of the mucosal γδ T cells receptor V region repertoire in patients with IgA nephropathy
3. Serum IgA and the production of IgA by peripheral blood and bone marrow lymphocytes in patients with primary IgA nephropathy: Evidence for the bone marrow as the source of mesangial IgA
4. Humoral immune response to influenza vaccination in patients with primary immunoglobulin A nephropathy. An analysis of isotype distribution and size of the influenza-specific antibodies
5. Increased and prolonged production of specific polymeric IgA following systemic immunisation with tetanus toxoid in IgA nephropathy
6. Increase of both circulating Th1 and Th2 T lymphocyte subsets in IgA nephropathy
7. Oligoclonally expanding γδ T lymphocytes induce IgA switching in IgA nephropathy
8. T and B cell responses following immunisation with tetanus toxoid in IgA nephropathy
9. Generation of human γδ T-cell repertoires
10. Subpopulations of T alpha cells in patients with IgA nephropathy: Correlation between T apha 4 cells andin vitro IgA production
11. Studies of the molecular basis of IgA production, subclass regulation and class-switch recombination in IgA nephropathy patients
12. Profiles of immunoregulatory cytokine production in vitro in patients with IgA nephropathy and their kindred
13. Evidence for genetic factors in the development and progression of IgA nephropathy
14. IgA nephropathy, the most common cause of glomerulonephritis, is linked to 6q22-23
15. The TDT and other family-based tests for linkage disequilibrium and association