Neurotoxicity with leukoencephalopathy after a single intravenous high dose of methotrexate in a patient with lymphoma

Acta Haematologica

Volumn 107, Issue 3, 2002, Pages 185-186

  Cohen, Yossi ^a   Lossos, Alex ^a   Polliack, Aaron ^a  

^a HADASSAH HEBREW UNIVERSITY MEDICAL CENTER   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

FOLINIC ACID; METHOTREXATE;

ADULT; ARTICLE; BURKITT LYMPHOMA; CASE REPORT; DISEASE COURSE; DRUG BLOOD LEVEL; DRUG EFFECT; EARLY DIAGNOSIS; HUMAN; LABORATORY TEST; LEUKOENCEPHALOPATHY; MALE; NEUROTOXICITY; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL;

ADULT; ANTINEOPLASTIC AGENTS; BRAIN DISEASES; BURKITT LYMPHOMA; HUMANS; MAGNETIC RESONANCE IMAGING; MALE; METHOTREXATE;

EID: 0036236862     PISSN: 00015792     EISSN: None     Source Type: Journal    
DOI: 10.1159/000057639     Document Type: Article

References (8)

1. Methotrexate treatment protocols and the central nervous system: Significant cure with significant neurotoxicity
2. Toxic leukoencephalopathy
3. Toxic leukoencephalopathy
4. Methotrexate-induced leukoencephalopathy is treatable with high-dose folinic acid: A case report and analysis of the literature
5. Nuclear magnetic resonance abnormalities of the cerebral white matter in children with acute lymphoblastic leukemia and malignant lymphoma during and after central nervous system prophylactic treatment with intrathecal methotrexate
6. Acute neurotoxicity in children with B-precursor acute lymphoid leukemia: An association with intermediate-dose intravenous methotrexate ad intrathecal triple therapy - A Pediatric Oncology Group study
7. Treatment-related white matter changes in cancer patients
8. Leukoencephalopathy following high-dose IV methotrexate chemotherapy with leucovorin rescue