Delta ribozyme benefits from a good stability in vitro that becomes outstanding in vivo

RNA

Volumn 8, Issue 4, 2002, Pages 464-477

  Lévesque, Dominique ^a   Choufani, Sanaa ^a   Perreault, Jean Pierre ^a  

^a UNIVERSITÉ DE SHERBROOKE   (Canada)

Author keywords

Gene therapy; Molecular evolution; Ribozyme; RNA stability; RNA structure function

Indexed keywords

DELTA RIBOZYME; NUCLEASE; PHOSPHODIESTERASE; RIBOZYME; UNCLASSIFIED DRUG;

ADAPTATION; ARTICLE; AUTORADIOGRAPHY; ELECTROPORATION; ENZYME CONFORMATION; ENZYME LOCALIZATION; GENE INACTIVATION; GENE THERAPY; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; HYDROLYSIS; MOLECULAR EVOLUTION; MOLECULAR STABILITY; MUTAGENESIS; NATURAL SELECTION; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN SECONDARY STRUCTURE; RNA STABILITY; RNA STRUCTURE; RNA SYNTHESIS; STRUCTURE ACTIVITY RELATION;

BASE SEQUENCE; CATALYTIC DOMAIN; CELLS, CULTURED; HEPATITIS DELTA VIRUS; HUMANS; MOLECULAR SEQUENCE DATA; MUTAGENESIS; RNA STABILITY; RNA, CATALYTIC; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0036235582     PISSN: 13558382     EISSN: None     Source Type: Journal    
DOI: 10.1017/S1355838202020289     Document Type: Article

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