Carcinogenesis at the gastroesophageal junction: Free radicals at the frontier

Gastroenterology

Volumn 122, Issue 5, 2002, Pages 1518-1520

  Spechler, Stuart Jon ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ASCORBIC ACID; DNA; FREE RADICAL; HYDROXYL RADICAL; NITRATE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE;

DIETARY INTAKE; EDITORIAL; HELICOBACTER PYLORI; HUMAN; LOWER ESOPHAGUS SPHINCTER; PRIORITY JOURNAL; STOMACH CANCER; STOMACH CARCINOGENESIS; STOMACH JUICE; STOMACH MUCOSA; STOMACH PH;

EID: 0036234149     PISSN: 00165085     EISSN: None     Source Type: Journal    
DOI: 10.1053/gast.2002.33368     Document Type: Article

References (25)

1. Changing patterns in the incidence of esophageal and gastric carcinoma in the United States
2. Unbuffered highly acidic gastric juice exists at the gastroesophageal junction after a meal
3. Dietary nitrate generates potentially mutagenic concentrations of nitric oxide at the gastroesophageal junction
4. The pharmacology of dietary nitrate and the origin of urinary nitrate
5. Chemical generation of nitric oxide in the mouth from the enterosalivary circulation of dietary nitrate
6. Chemical synthesis of nitric oxide in the stomach from dietary nitrate in humans
7. Reaction of salivary nitrite with gastric acid and vitamin C relevant to proximal gastric cancer and Barrett's oesophagus
8. The L-arginine-nitric oxide pathway
9. Potential genotoxicity of chronically elevated nitric oxide: A review
10. Role of nitric oxide in genotoxicity: Implications for carcinogenesis
11. Inflammatory cytokines induce DNA damage and inhibit DNA repair in cholangiocarcinoma cells by a nitric oxide-dependent mechanism
12. Biochemistry of nitric oxide and its redox-activated forms
13. Molecular cloning, structure, and chromosomal localization of the human inducible nitric oxide synthase gene
14. Nitrates, nitrites, and gastric cancer in Great Britain
15. Association between body mass and adenocarcinoma of the esophagus and gastric cardia
16. Gastric juice ascorbic acid: Effects of disease and implications for gastric carcinogenesis
17. Induction and promotion of forestomach tumors by sodium nitrite in combination with ascorbic acid or sodium ascorbate in rats with or without N-methyl-N′-nitro-N-nitrosoguanidine pre-treatment
18. Intragastric nitric oxide production in humans: Measurements in expelled air
19. Omeprazole, Helicobacter pylori status, and alterations in the intragastric milieu facilitating bacterial N-nitrosation
20. Helicobacter pylori and gastric carcinogenesis
21. Symptomatic gastroesophageal reflux as a risk factor for esophageal adenocarcinoma
22. Vitamin C concentration in gastric juice before and after anti-Helicobacter pylori treatment
23. Effect of Helicobacter pylori and its eradication on gastric juice ascorbic acid
24. Omeprazole and dietary nitrate independently affects levels of vitamin C and nitrite in gastric juice
25. An inverse relation between cagA+ strains of Helicobacter pylori infection and risk of esophageal and gastric cardia adenocarcinoma