Improvement and characterization of the in vitro dissolution behavior of sulindac by complexation with β-cyclodextrin

Acta Pharmaceutica

Volumn 52, Issue 1, 2002, Pages 9-18

  Obaidat, Aiman A ^a   Matalqah, Sina M ^a   Najib, Naji M ^a  

^a JORDAN UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Jordan)

Author keywords

Dissolution; DSC; Inclusion complex; Sulindac; X ray diffraction; cyclodextrin

Indexed keywords

BETA CYCLODEXTRIN; SULINDAC;

ARTICLE; COMPARATIVE STUDY; COMPLEX FORMATION; DIFFERENTIAL SCANNING CALORIMETRY; DISSOLUTION; DRUG BIOAVAILABILITY; DRUG DEGRADATION; DRUG SOLUBILITY; EVAPORATION; GASTROINTESTINAL SYMPTOM; HUMAN; IN VITRO STUDY; PH; PHYSICAL CHEMISTRY; PRECIPITATION; SOLID STATE; X RAY DIFFRACTION;

EID: 0036230850     PISSN: 13300075     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (15)

1. Pharmaceutical applications of cyclodextrins 1. Drug solubilization and stabilization
2. Cyclodextrins: Their future in drug formulation
3. Physicochemical characterization and dissolution of norfloxacin-cyclodextrin inclusion compounds and PEG solid dispersions
4. Preparation and evaluation of ketokenazole-β-cyclodextrin multicomponent complexes
5. Improvement of the in vitro dissolution characteristics of famotidine by inclusion in β-cyclodextrin
6. Study of the dissolution characteristics of oxazepam via complexation with β-cyclodextrin
7. Biopharmaceutical stability of glibornuride-β-cyclodextrin inclusion complex after one year of storage
8. Reduction in the ulcergenicity of naproxen by complexation with β-cyclodextrin
9. Inclusion complexes of terfinadine-cyclodextrins
10. Improvement in solubility and stability of thalidomide upon complexation with hydroxypropyl-β-cyclodextrin
11. Physical characteristics of inclusion compounds of 5-ASA in α- and β-cyclodextrin
12. Solubility and solubilization properties of non-steroidal anti-inflammatory drugs
13. Gastric bleeding and gastric secretion with sulindac and naproxen
14. Phase solubility techniques
15. Solubilization and interaction of sulindac with β-cyclodextrin in the solid state and in aqueous solution