DNA supercoiling in Escherichia coli is under tight and subtle homeostatic control, involving gene-expression and metabolic regulation of both topoisomerase I and DNA gyrase

European Journal of Biochemistry

Volumn 269, Issue 6, 2002, Pages 1662-1669

  Snoep, Jacky L ^a,b   Van Der Weijden, Coen C ^a   Andersen, Heidi W ^b,c   Westerhoff, Hans V ^a,d   Jensen, Peter Ruhdal ^c  

^a VU UNIVERSITY AMSTERDAM   (Netherlands)

^b STELLENBOSCH UNIVERSITY   (South Africa)

^c TECHNICAL UNIVERSITY OF DENMARK   (Denmark)

^d STELLENBOSCH INSTITUTE FOR ADVANCED STUDY   (South Africa)

Author keywords

Hierarchical control analysis (HCA); Homeostasis coefficient; Metabolic control analysis (MCA)

Indexed keywords

DNA TOPOISOMERASE; DNA TOPOISOMERASE (ATP HYDROLYSING);

ARTICLE; CONTROLLED STUDY; DNA STRUCTURE; DNA SUPERCOILING; ENZYME ACTIVITY; ESCHERICHIA COLI; GENE EXPRESSION; GENE EXPRESSION REGULATION; HOMEOSTASIS; METABOLIC REGULATION; NONHUMAN; PLASMID; PRIORITY JOURNAL; PROKARYOTE; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; REGULATORY MECHANISM;

BASE SEQUENCE; DNA GYRASE; DNA PRIMERS; DNA TOPOISOMERASES, TYPE I; DNA, BACTERIAL; DNA, SUPERHELICAL; ESCHERICHIA COLI; GENE EXPRESSION; HOMEOSTASIS;

ESCHERICHIA COLI; NEGIBACTERIA; PROKARYOTA;

EID: 0036227648     PISSN: 00142956     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1432-1327.2002.02803.x     Document Type: Article

References (27)

1. Supercoils in prokaryotic DNA restrained in vivo
2. DNA topoisomerases
3. Relaxation of transcription-induced negative supercoiling is an essential function of Escherichia coli DNA topoisomerase I
4. Escherichia coli DNA topoisomerase I inhibits R-loop formation by relaxing transcription-induced negative supercoiling
5. Roles of topoisomerases in maintaining steady state DNA supercoiling in Escherichia coli
6. Regulation of the genes for E. coli DNA gyrase: Homeostatic control of DNA supercoiling
7. Interaction between DNA and an Escherichia coli protein omega
8. The intrinsic ATPase of DNA gyrase
9. Regulation of Escherichia coli DNA topoisomerase I gene by DNA supercoiling
10. Gyrase inhibitors can increase gyrA expression and DNA supercoiling
11. Extensive regulation compromises the extent to which DNA gyrase controls DNA supercoiling and growth rate of Escherichia coli
12. Improved M13 phage cloning vectors and host strains: Nucleotide sequences of the M13mp18 and pUC19 vectors
13. Quantitative evaluation of Escherichia coli host strains for tolerance to cytosine methylation in plasmid and phage recombinants
14. Analysis of gene control signals by DNA fusion and cloning in Escherichia coli
15. Culture medium for Enterobacteria
16. Excess capacity of H+-ATPase and inverse respiratory control in Escherichia coli
17. Carbon and energy metabolism of atp mutants of Escherichia coli
18. DNA supercoiling depends on the phosphorylation potential in Escherichia coli
19. The use of lac-type promoters in control analysis
20. The control of flux
21. A linear steady-state treatment of enzymatic chains. General properties, control and effector strength
22. Control of bacterial DNA supercoiling
23. DNA supercoiling by DNA gyrase. A static head analysis
24. Thermodynamics of complexity - The live cell
25. Building the cellular puzzle. Control in multi-level reaction networks
26. Fusions of the Escherichia coli gyrA and gyrB control regions to the galactokinase gene are inducible by coumermycin treatment