Increased incidence of spontaneous apoptosis in the bone marrow of hyperdiploid childhood acute lymphoblastic leukemia

Experimental Hematology

Volumn 30, Issue 4, 2002, Pages 333-339

  Zhang, Yili ^a   Lu, Jinhua ^a   van den Berghe, Janette ^b   Lee, Szu Hee ^a  

^a NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^b ROYAL UNIVERSITY HOSPITAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ACUTE LYMPHOBLASTIC LEUKEMIA; APOPTOSIS; ARTICLE; BONE MARROW; CELL POPULATION; CHILDHOOD LEUKEMIA; CHROMOSOME; CLINICAL ARTICLE; CONTROLLED STUDY; DIPLOIDY; DNA CONTENT; DNA DEGRADATION; DNA DETERMINATION; FEMALE; GENETIC ANALYSIS; HUMAN; HUMAN CELL; INCIDENCE; LYMPHOBLAST; MALE; PRESCHOOL CHILD; PRIORITY JOURNAL; PROGNOSIS;

APOPTOSIS; BONE MARROW; CHILD, PRESCHOOL; CYTOGENETIC ANALYSIS; DIPLOIDY; FEMALE; HUMANS; IN SITU NICK-END LABELING; INCIDENCE; INFANT; LEUKEMIA, B-CELL, ACUTE; LEUKEMIA, LYMPHOCYTIC, ACUTE, L1; MALE; PLOIDIES; PROGNOSIS;

EID: 0036221447     PISSN: 0301472X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0301-472X(02)00771-3     Document Type: Article

References (33)

1. Trends in cancer incidence among children in the U.S.
2. Uniform approach to risk classification and treatment assignment for children with acute lymphoblastic leukemia
3. Prognostic implications of chromosomal findings in acute lymphoblastic leukaemia at diagnosis
4. Chromosomal abnormalities identify high-risk and low-risk patients with acute lymphoblastic leukemia
5. Prognostic importance of structural chromosomal abnormalities in children with hyperdiploid (greater than 50 chromosomes) acute lymphoblastic leukaemia
6. Accumulation of high levels of methotrexate polyglutamates in lymphoblasts from children with hyperdiploid (greater than 50 chromosomes) B-lineage acute lymphoblastic leukemia: A pediatric oncology group study
7. Blast cell methotrexate-polyglutamate accumulation in vivo differs by lineage, ploidy and methotrexate dose in acute lymphoblastic leukemia
8. Favourable prognosis of hyperdiploid common acute lymphoblastic leukemia may be explained by sensitivity to antimetabolites and other drugs: Results of an in vitro study
9. Stroma-supported culture of childhood B-lineage acute lymphoblastic leukaemia cells predicts treatment outcome
10. Hyperdiploid acute lymphoblastic leukemia with 51 to 65 chromosomes: A distinct biological entity with a marked propensity to undergo apoptosis
11. Detection of hyperdiploid karyotypes (>50 chromosomes) in childhood acute lymphoblastic leukemia (ALL) using fluorescence in situ hybridization (FISH)
12. The clinical and histopathological significance of Feulgen DNA-values in transitional cell carcinoma of the human urinary bladder
13. Prognostic significance of nuclear DNA content in serous ovarian tumors
14. Prognostic value of nuclear DNA content in medullary thyroid carcinoma
15. Ploidy level determinations in high-grade and low-grade malignant variants of prostatic carcinoma
16. The Reed-Sternberg cells of Hodgkin disease are clonal
17. Apoptosis: A basic biological phenomenon with wide-ranging implications in tissue kinetics
18. Chromatin cleavage in apoptosis: Association with condensed chromatin morphology and dependence on macromolecular synthesis
19. Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation
20. Identification of programmed cell death in situ via specific labelling of nuclear DNA fragmentation
21. Proposals for the classification of the acute leukaemia. French-American-British (FAB) Co-operative Group
22. Static cytometry identifies hyperdiploid childhood ALL
23. Different patterns of apoptosis of HL-60 cells induced by cycloheximide and camptothecin
24. Heterogeneity of hyperdiploid (51-67) childhood acute lymphoblastic leukaemia
25. Staging of acute lymphoblastic leukemia
26. Why does childhood lymphoblastic leukemia with hyperdiploidy show a favorable prognosis?
27. Phenotypic and karyotypic properties of hyperdiploid acute lymphoblastic leukaemia of childhood
28. Near-triploid and near-tetraploid acute lymphoblastic leukemia of childhood
29. Biochemical and genetic control of apoptosis: Relevance to normal hematopoiesis and hematological malignancies
30. Prognostic importance of chromosome number in 136 untreated children with acute lymphoblastic leukemia
31. Cytogenetics of acute lymphoblastic leukaemia in children as a factor in the prediction of long-term survival
32. Aneuploidy and percentage of S-phase cells determined by flow cytometry correlate with cell phenotype in childhood acute leukemia