Menaquinone-4 in breast milk is derived from dietary phylloquinone

British Journal of Nutrition

Volumn 87, Issue 3, 2002, Pages 219-226

  Thijssen, H H W ^a   Drittij, M J ^a   Vermeer, C ^a   Schoffelen, E ^b  

^a MAASTRICHT UNIVERSITY   (Netherlands)

^b Centre of Midwifery   (Netherlands)

Author keywords

Breastmilk; Menaquinone 4; Phylloquinone; Prophylaxis; Vitamin K

Indexed keywords

ALPHA TOCOPHEROL; MENATETRENONE; PHYTOMENADIONE; VITAMIN K GROUP;

ARTICLE; BREAST MILK; CLINICAL TRIAL; COLOSTRUM; CONCENTRATION (PARAMETERS); CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIET SUPPLEMENTATION; DOSE RESPONSE; DRUG BLOOD LEVEL; DRUG MILK LEVEL; FEMALE; HUMAN; INFANT; LACTATION; MATERNAL NUTRITION; MILK LEVEL; POSTNATAL CARE; PROPHYLAXIS; RANDOMIZED CONTROLLED TRIAL; VITAMIN BLOOD LEVEL; VITAMIN SUPPLEMENTATION;

ANTIFIBRINOLYTIC AGENTS; DIETARY SUPPLEMENTS; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; HUMANS; MILK, HUMAN; VITAMIN E; VITAMIN K 1; VITAMIN K 2;

EID: 0036219694     PISSN: 00071145     EISSN: None     Source Type: Journal    
DOI: 10.1079/BJNBJN2001505     Document Type: Article

References (38)

1. Über die umwandlung von phylloquinon (vitamin K1) in vitamin K2(20) im tierkörper
2. Vitamin E, lipid fractions, and fatty acid composition of colostrum, transitional milk, and mature milk: An international comparative study
3. Dietary intake and adequacy of vitamin K
4. Vitamin K in preterm breastmilk with maternal supplementation
5. Comparison of the vitamins K1, K2, and K3 as cofactors for the hepatic vitamin K-dependent carboxylase
6. Vitamin A and E content of human milk at early stages of lactation
7. The production of menaquinones (vitamin K2) by intestinal bacteria and their role in maintaining coagulation homeostasis
8. Prevention of vitamin K deficiency bleeding: Efficacy of different multiple oral dose schedules of vitamin K
9. Conversion of dietary phylloquinone to tissue menaquinone-4 in rats is not dependent on gut bacteria
10. Isolation and characterization of menaquinone-4 as a product of menadione metabolism in chicks and rats
11. Variations of phylloquinone concentration in human milk at various stages of lactation and in cow's milk at various seasons
12. Vitamin K deficiency and hemorrhage in infancy
13. Improving the vitamin K status of breastfeeding infants with maternal vitamin K supplements
14. Human lactation: Maternal transfer of dietary triglycerides labeled with stable isotopes
15. The pharmacokinetics and lipoprotein fraction distribution of intramuscular vs oral vitamin K1 supplementation in women of childbearing age: Effects on hemostasis
16. Liquid-chromatographic determination of vitamin K1 in plasma, with fluorometric detection
17. Changing patterns of human milk lipids in the course of lactation and during the day
18. Distribution of K vitamins (phylloquinone and menaquinones) in human placenta and maternal and umbilical cord plasma
19. Vitamin K in milk and infant formulas: Determination and distribution of phylloquinone and menaquinone-4
20. Vitamin K intake and osteocalcin levels in women with and without aortic atherosclerosis: A population-based study
21. Menaquinone production and utilization in germ-free rats after inoculation with specific organisms
22. Physiology of pregnancy and nutrient metabolism
23. Transport of vitamin K to bone in humans
24. Vitamin E
25. Studies in human lactation: Milk volumes in lactating women during the onset of lactation and full lactation
26. Absorption, tissue distribution and bioactivity of vitamin K and related compounds in the rat
27. Intestinal flora is not an intermediate in the phylloquinone-menaquinone-4 conversion in the rat
28. Production of Menaquinones by intestinal anaerobes
29. Vitamin K metabolism and nutriture
30. Vitamin K deficiency bleeding (VKDB) in infancy
31. The importance of menaquinones in human nutrition
32. Vitamin K distribution in rat tissue: Dietary phylloquinone is a source of tissue menaquinone-4
33. Vitamin K status in human tissues: Tissue-specific accumulation of phylloquinone and menaquinone-4
34. Phylloquinone and menaquinone-4 distribution in rats: Synthesis rather than uptake determines menaquinone-4 organ concentrations
35. Dietary reference intakes: Vitamin A, vitamin K, arsenic, boron, copper, iodine, iron, manganese, molybdenum, nickel, silicon, vanadium and zinc
36. Comparative metabolism and requirement of vitamin K in chicks and rats
37. Vitamin K1 content of maternal milk: Influence of the stage of lactation, lipid composition, and vitamin K1 supplements given to the mother