Biosynthesis of the trehalase inhibitor trehazolin

Journal of Antibiotics

Volumn 55, Issue 3, 2002, Pages 263-269

  Sugiyama, Yasumasa ^a   Nagasawa, Hiromichi ^a   Suzuki, Akinori ^a   Sakuda, Shohei ^a  

^a UNIVERSITY OF TOKYO   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ALLOSAMIDIN; AMIDINE; ARGININE; ARISTEROMYCIN; CARBON; CARBON 13; CYCLOPENTANE; DEUTERIUM; FRUCTOSE; GLUCOSE; GLYCOSIDASE INHIBITOR; GUANIDINE; HYDROGEN; NITROGEN; NITROGEN 15; OXAZOLINE DERIVATIVE; PACTAMYCIN; TREHALASE; TREHAZOLIN; UNCLASSIFIED DRUG;

ARTICLE; BIOSYNTHESIS; CHEMICAL BOND; CHEMICAL LABELING; CONTROLLED STUDY; DRUG STRUCTURE; MICROMONOSPORA; MICROMONOSPORA CORIACEA; NONHUMAN; PRECURSOR; PRIORITY JOURNAL;

MICROMONOSPORA CORIACEA;

EID: 0036215652     PISSN: 00218820     EISSN: None     Source Type: Journal    
DOI: 10.7164/antibiotics.55.263     Document Type: Article

References (19)

1. Trehazolin, a new trehalase inhibitor
2. Inhibitors pig kidney trehalase
3. Trehazolin, a slow, tight-binding inhibitor of silkworm trehalase
4. Isolation of trehalamine, the aglycon of trehazolin, from microbial broths and characterization of trehazolin related compounds
5. Chemistry and biology of trehazolins
6. Synthesis and biological activity of natural aminocyclitol glycosidase inhibitors: Mannostatins, trehazolin, allosamidins, and their analogs
7. The biosynthesis of carbocyclic nucleosides
8. 7N unit
9. Prokaryotic hopanoids: The biosynthesis of the bacteriohopane skeleton. Formation of isoprenic units from two distinct acetate pools and a novel type of carbon/carbon linkage between a triterpene and D-ribose
10. Biosynthesis of the nucleoside antibiotic aristeromycin
11. Biosynthetic studies on the chitinase inhibitor, allosamidin. Origin of the carbon and nitrogen atoms
12. Biosynthetic studies on the cyclopentane ring formation of allosamizoline, an aminocyclitol component of the chitinase inhibitor allosamidin
13. Enzymatic carbocycle formation in microbial secondary metabolism. The mechanism of the 2-deoxy-scyllo-inosose synthase reaction as a crucial step in the 2-deoxystreptamine biosynthesis in Streptomyces fradiae
14. Stereochemistry of the myo-inositol-1-phosphate synthase reaction
15. Mechanism of the aldose-ketose isomerase reactions
16. The biosynthesis of the streptolidine moiety in streptothricin F
17. Glucose is a precursor of 1-deoxynojirimycin and 1-deoxymannonojirimycin in Streptomyces subrutilus
18. Mechanistic studies of the biosynthesis of 3,6-dideoxyhexoses in Yersinia pseudotuberculosis
19. Synthesis of D-glucose-6-t