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Fundamental and Clinical Pharmacology

Volumn 16, Issue 1, 2002, Pages 39-47

5-Fluorocytosine-related bone-marrow depression and conversion to fluorouracil: A pilot study

(4) Vermes, András a Guchelaar, Henk Jan a Van Kuilenburg, Andre B P a Dankert, Jacob a

a UNIVERSITY OF AMSTERDAM (Netherlands)

Author keywords

Bone marrow depression; Conversion; Fluorocytosine (5 FC); Fluorouracil (5 FU); Toxicity; Fluoro alanine (FBAL)

Indexed keywords

ALPHA FLUORO BETA ALANINE; AMPHOTERICIN B; FLUCYTOSINE; FLUOROURACIL;

ADULT; AGED; ARTICLE; BIOASSAY; BIOLOGICAL MONITORING; BLOOD LEVEL; BLOOD SAMPLING; BONE MARROW DEPRESSION; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE ASSOCIATION; DISEASE COURSE; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; FEMALE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; INTENSIVE CARE UNIT; INTESTINE FLORA; LEUKOCYTE; LEUKOCYTE COUNT; LEUKOCYTOSIS; LEUKOPENIA; MALE; MYCOSIS; PILOT STUDY; PRIORITY JOURNAL; QUANTITATIVE ASSAY; THROMBOCYTE; THROMBOCYTE COUNT; THROMBOCYTOPENIA; TOXICITY;

ADULT; AGED; BETA-ALANINE; BIOTRANSFORMATION; BONE MARROW; CANDIDIASIS; FEMALE; FLUCYTOSINE; FLUOROURACIL; HUMANS; INJECTIONS, INTRAVENOUS; LEUKOCYTE COUNT; LEUKOPENIA; MALE; MENINGITIS, CRYPTOCOCCAL; MIDDLE AGED; MODELS, THEORETICAL; PILOT PROJECTS; PLATELET COUNT; THROMBOCYTOPENIA;

EID: 0036213371 PISSN: 07673981 EISSN: None Source Type: Journal
DOI: 10.1046/j.1472-8206.2002.00064.x Document Type: Article

Times cited : (10)

References (36)

1
- 0000787521
- The synthesis of 5-fluoropyrimidines
- (1957) J. Am. Chem. Soc. , vol.79 , pp. 4559-4560
- Duschinsky, R.¹ Pleven, E.² Heidelberger, C.³

2
- 0011234930
- Studies on fluorinated pyrimidines. II. Effects on transplanted tumors
- (1958) Cancer Res. , vol.18 , pp. 305-317
- Heidelberger, C.¹ Griesbach, L.² Montag, B.J.³

3
- 84883849102
- Chemotherapeutic activity of 5-fluorocytosine
- (1964) Antimicrob. Agents Chemother. , vol.3 , pp. 566-568
- Grunberg, E.¹ Titsworth, E.² Bennett, M.³

4
- 0014425886
- Treatment of Candida species and Cryptococcus meningitis with 5-fluorocytosine. A new antifungal agent
- (1968) JAMA , vol.206 , pp. 830-832
- Tassel, D.¹ Madoff, M.A.²

5
- 0014396343
- 5-Fluorocytosine in human cryptococcosis
- (1969) Antimicrob. Agents Chemother. , vol.8 , pp. 344-346
- Utz, J.P.¹ Tynes, B.S.² Shadomy, H.J.³ Duma, R.J.⁴ Kannan, M.M.⁵ Mason, K.N.⁶

6
- 0023908371
- Clinical use of systemic antifungal agents
- (1988) Clin. Pharm. , vol.7 , pp. 424-438
- Benson, J.M.¹ Nahata, M.C.²

7
- 0020691284
- Antifungal agents used in systemic mycoses. Activity and therapeutic use
- (1983) Drugs , vol.25 , pp. 41-62
- Graybill, J.R.¹ Craven, P.C.²

8
- 0018663921
- A comparison of amphotericin B alone and combined with flucytosine in the treatment of cryptococcal meningitis
- (1979) N. Engl. J. Med. , vol.301 , pp. 126-131
- Bennett, J.E.¹ Dismukes, W.E.² Duma, R.J.³

9
- 0026564314
- Evolving role of flucytosine in immunocompromised patients: New insights into safety, pharmacokinetics, and antifungal therapy
- (1992) Clin. Infect. Dis. , vol.15 , pp. 1003-1018
- Francis, P.¹ Walsh, T.J.²

10
- 0017579803
- Fluorocytosine
- (1977) Ann. Intern. Med. , vol.86 , pp. 319-321
- Bennett, J.E.¹

11
- 0017869837
- Mode of action of 5-fluorocytosine
- (1978) Biochem. Pharmacol. , vol.27 , pp. 703-707
- Diasio, R.B.¹ Bennett, J.E.² Myers, C.E.³

12
- 0001152911
- Mode of action of 5-fluorocytosine
- (1980) Rev. Inst. Pasteur Lyon , vol.13 , pp. 233-244
- Polak, A.¹ Scholer, H.J.²

13
- 0001902681
- Antimicrobial Agents. Antifungal Agents
- Hardman J.G., Limbird L.E., Molinoff P.B., Ruddon R.W., Goodman Gilman A. (Eds), McGraw-Hill Companies, New York, USA
- (1996) Goodman and Gilman's the Pharmacological Basis of Therapeutics, 9th edn. , pp. 1175-1190
- Bennett, J.E.¹

14
- 0002190941
- Fluorocytosine
- Speller D.C.E. (Ed.). John Wiley & Sons, New York, USA
- (1980) Antifungal Chemotherapy , pp. 35-106
- Scholer, H.J.¹

15
- 0020676253
- Mechanisms of action of 5-fluorocytosine
- (1983) Antimicrob. Agents Chemother. , vol.23 , pp. 79-85
- Waldorf, A.R.¹ Polak, A.²

16
- 0016255527
- Treatment of disseminated candidiasis with 5-fluorocytosine
- (1974) J. Infect. Dis. , vol.130 , pp. 155-159
- Eilard, T.¹ Alestig, K.² Wahlén, P.³

17
- 0017349264
- Bone marrow toxicity associated with 5-fluorocytosine therapy
- (1977) Antimicrob. Agents Chemother. , vol.11 , pp. 244-247
- Kauffman, C.A.¹ Frame, P.T.²

18
- 0023634292
- Toxicity of amphotericin B plus flucytosine in 194 patients with cryptococcal meningitis
- (1987) Am. J. Med. , vol.83 , pp. 236-242
- Stamm, A.M.¹ Diasio, R.B.² Dismukes, W.E.³

19
- 0016837061
- Therapy of cryptococcosis with a combination of flucytosine and amphotericin B
- (1975) J. Infect. Dis. , vol.132 , pp. 368-373
- Utz, J.P.¹ Garriques, I.L.² Sande, M.A.³

20
- 0033961388
- Flucytosine: Correlation between toxicity and pharmacokinetic parameters
- (2000) Chemotherapy , vol.46 , pp. 86-94
- Vermes, A.¹ Van der Sijs, I.H.² Guchelaar, H.-J.³

21
- 0018080634
- Evidence for conversion of 5-fluorocytosine to 5-fluorouracil in humans: Possible factor in 5-fluorocytosine clinical toxicity
- (1978) Antimicrob. Agents Chemother. , vol.14 , pp. 903-908
- Diasio, R.B.¹ Lakings, D.E.² Bennett, J.E.³

22
- 0344109583
- Efficacy of intravenous continuous infusion of fluorouracil compared with bolus administration in advanced colorectal cancer
- (1998) J. Clin. Oncol. , vol.16 , pp. 301-308

23
- 0345596364
- Toxicity of fluorouracil compared in patients with advanced colorectal cancer: Effect of administration schedule and prognostic factors
- (1998) J. Clin. Oncol. , vol.16 , pp. 3537-3541

24
- 0023501122
- 19F nuclear magnetic resonance
- (1987) Drug Metab. Dispos. , vol.15 , pp. 718-724
- Vialaneix, J.P.¹ Malet-Martino, M.C.² Hoffmann, J.C.³ Pris, J.⁴ Martino, R.⁵

25
- 0019870367
- Identification of minor metabolites of 5-fluorocytosine in man by chemical ionization gas chromatography mass spectrometry
- (1981) Biomed. Mass Spectrom. , vol.8 , pp. 179-182
- Williams, K.M.¹ Duffield, A.M.² Christopher, R.K.³ Finlayson, O.J.⁴

26
- 0032961161
- An accelerated stability study of 5-flucytosine in intravenous solution
- (1999) Pharm. World Sci. , vol.21 , pp. 35-39
- Vermes, A.¹ Van der Sijs, I.H.² Guchelaar, H.-J.³

27
- 0025729771
- Flucytosine conversion to fluorouracil in humans: Does a correlation with gut flora status exist? A report of two cases using fluorine-19 magnetic resonance spectroscopy
- (1991) Infection , vol.19 , pp. 178-180
- Malet-Martino, M.C.¹ Martino, R.² De Forni, M.³ Andremont, A.⁴ Hartmann, O.⁵ Armand, J.P.⁶

28
- 0022649516
- Conversion of 5-fluorocytosine to 5-fluorouracil by human intestinal microflora
- (1986) Antimicrob. Agents Chemother. , vol.29 , pp. 44-48
- Harris, B.E.¹ Manning, B.W.² Federle, T.W.³ Diasio, R.B.⁴

29
- 0035062532
- Simultaneous determination of flucytosine and fluorouracil in human plasma by high-performance liquid chromatography
- (2001) Biomed. Chromatogr. , vol.15 , pp. 89-94
- Sastre Toraño, J.¹ Vermes, A.² Guchelaar, H.-J.³

30
- 0026580927
- MW\PHARM, an integrated software package for drug dosage regimen and therapeutic drug monitoring
- (1992) Comput. Biol. Med. , vol.22 , pp. 155-163
- Proost, J.H.¹ Meyer, D.K.F.²

31
- 0033647263
- Population pharmacokinetics of fluorocytosine: Comparison and validation of three models using STS, NPEM, and NONMEM
- (2000) Ther. Drug Monit. , vol.22 , pp. 676-687
- Vermes, A.¹ Mathôt, R.A.A.² Van der Sijs, I.H.³ Dankert, J.⁴ Guchelaar, H.-J.⁵

32
- 0003662458
- University of California at Berkeley, San Francisco, USA
- (2000) Berkeley Madonna, Version 7.02
- Macey, R.¹ Oster, G.²

33
- 0004261410
- Appleton & Lange, Norwalk, USA
- (1994) Cancer Chemotherapy Handbook, 2nd edn. , pp. 500-515
- Dorr, R.T.¹ Von Hoff, D.D.²

34
- 0033869563
- Flucytosine: A review of its pharmacology, clinical indications, pharmacokinetics, toxicity and drug interactions
- (2000) J. Antimicrob. Chemother. , vol.46 , pp. 171-179
- Vermes, A.¹ Guchelaar, H.-J.² Dankert, J.³

35
- 0031901763
- Long-term weekly treatment of colorectal metastatic cancer with fluorouracil and leucovorin: Results of a multicentric prospective trial of fluorouracil dosage optimization by pharmacokinetic monitoring in 152 patients
- (1998) J. Clin. Oncol. , vol.16 , pp. 1470-1478
- Gamelin, B.¹ Biosdron-Celle, M.² Delva, R.³

36
- 0035812208
- Simultaneous determination of F-β-alanine and β-alanine in plasma and urine with dual-column reversed-phase high-performance liquid chromatography
- (2001) J. Chromatogr. B , vol.759 , pp. 51-61
- Van Kuilenburg, A.B.P.¹ Stroomer, A.E.M.² Peters, G.J.³ Van Gennip, A.H.⁴

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