Effects of carvedilol on cardiac function and cardiac adrenergic neuronal damage in rats with dilated cardiomyopathy

Journal of Nuclear Medicine

Volumn 43, Issue 4, 2002, Pages 531-535

  Watanabe, Kenichi ^a   Takahashi, Toshihiro ^a   Nakazawa, Mikio ^a   Wahed, Mir I I ^a   Fuse, Koichi ^a   Tanabe, Naohito ^a   Kodama, Makoto ^a   Aizawa, Yoshifusa ^a   Ashino, Hiroki ^a   Tazawa, Shusaku ^a  

^a NIIGATA UNIVERSITY OF PHARMACY AND APPLIED LIFE SCIENCES   (Japan)

Author keywords

blocker; 125I MIBG; Carvedilol; Dilated cardiomyopathy; Heart failure

Indexed keywords

(3 IODOBENZYL)GUANIDINE I 125; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CARVEDILOL;

ADRENERGIC NERVE CELL; ADRENERGIC SYSTEM; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; HEART DILATATION; HEART FAILURE; HEART FUNCTION; HEART INNERVATION; HEMODYNAMICS; HISTOPATHOLOGY; IMAGE ANALYSIS; MALE; NERVE CELL LESION; NONHUMAN; PRIORITY JOURNAL; RAT; SURVIVAL RATE;

3-IODOBENZYLGUANIDINE; ADRENERGIC BETA-ANTAGONISTS; ADRENERGIC FIBERS; ANIMALS; AUTOIMMUNE DISEASES; AUTORADIOGRAPHY; CARBAZOLES; CARDIOMYOPATHY, DILATED; FIBROSIS; HEART; HEMODYNAMIC PROCESSES; MALE; MYOCARDITIS; MYOCARDIUM; ORGAN SIZE; PROPANOLAMINES; RADIOPHARMACEUTICALS; RATS; RATS, INBRED LEW; VASODILATOR AGENTS;

EID: 0036213249     PISSN: 01615505     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (28)

1. Idiopathic dilated cardiomyopathy in the young: Clinical profile and natural history
2. Idiopathic dilated cardiomyopathy: Analysis of 152 necropsy patients
3. Acute myocarditis in the spectrum of acute dilated cardiomyopathies: Clinical features, histologic correlates, and clinical outcome
4. An animal model of congestive (dilated) cardiomyopathy: Dilatation and hypertrophy of the heart in the chronic stage in DBA/2 mice with myocarditis caused by encephalomyocarditis virus
5. Ongoing enterovirus-induced myocarditis is associated with persistent heart muscle infection: Quantitative analysis of virus replication, tissue damage, and inflammation
6. Giant cell versus lymphocytic myocarditis: A comparison of their clinical features and long-term outcomes
7. A novel experimental model of giant cell myocarditis induced in rats by immunization with cardiac myosin fraction
8. Rat dilated cardiomyopathy after autoimmune giant cell myocarditis
9. Low dose carvedilol inhibits progression of heart failure in rats with dilated cardiomyopathy
10. The pharmacology of carvedilol
11. Studies on the mechanism of arterial vasodilation produced the novel antihypertensive agent, carvedilol
12. Carvedilol: A novel cardiovascular drug with multiple actions
13. Carvedilol, a novel multiple action antihypertensive agent with antioxidant activity and the potential for myocardial and vascular protection
14. The effect of carvedilol on morbidity and mortality in patients with chronic heart failure
15. Safety and efficacy of carvedilol in severe heart failure
16. Carvedilol, a new vasodilator and β-adrenoceptor antagonist, is an antioxidant and free radical scavenger
17. Cardioprotective effects of carvedilol, a novel β-adrenoceptor antagonist with vasodilation properties, in anaesthetized minipigs: Comparison with propranolol
18. Myocardial imaging in man with I-123 meta-iodobenzylguanidine
19. Abnormal I-123-metaiodobenzylguanidine myocardial washout and distribution may reflect myocardial adrenergic derangement in patients with congestive cardiomyopathy
20. Iodine-123-metaiodobenzylguanidine images reflect intense myocardial adrenergic nervous activity in congestive heart failure independent of underlying cause
21. Detection of abnormal cardiac adrenergic neuron activity in adriamycin-induced cardiomyopathy with I-125-metaiodobenzylguanidine
22. Prognostic value of cardiac metaiodobenzylguanidine imaging in patients with heart failure
23. Recovery of the cardiac adrenergic nervous system after long-term β-blocker therapy in idiopathic dilated cardiomyopathy: Assessment by increase in myocardial 123-I-metaiodobenzylguanidine uptake
24. Studies with radioactive di-azo dyes
25. Decreased 123-I MIBG uptake and increased clearance in various cardiac diseases
26. Iodine-131 metaiodobenzylguanidine intra- and extravesicular accumulation in the rat heart
27. Metaiodobenzylguanidine as an index of atrioventricular nodal adrenergic activity
28. Washout of I-123 meta-iodobenzylguanidine for assessing cardiac sympathetic activity with progression of hypertension in Dahl salt-sensitive rats