Reliability and efficiency of interphase-FISH with α-satellite probe for detection of aneuploidy

Genetic Counseling

Volumn 13, Issue 1, 2002, Pages 11-17

  Acar, Hasan ^a   Yildirim, M S ^a   Kaynak, M ^a  

^a SELCUK UNIVERSITY   (Turkey)

Author keywords

Down syndrome; FISH; Trisomy 21

Indexed keywords

SATELLITE DNA;

ANEUPLOIDY; ARTICLE; CENTROMERE; CHILD; CHROMOSOME 13; CHROMOSOME 21; CONTROLLED STUDY; DNA PROBE; DNA SEQUENCE; DOWN SYNDROME; FEMALE; FLUORESCENCE IN SITU HYBRIDIZATION; HUMAN; HUMAN CELL; INFANT; INTERPHASE; MAJOR CLINICAL STUDY; MALE; METAPHASE CHROMOSOME; RELIABILITY; TRISOMY 21;

CASE-CONTROL STUDIES; CHILD, PRESCHOOL; DNA PROBES; DNA, SATELLITE; DOWN SYNDROME; FEMALE; HUMANS; IN SITU HYBRIDIZATION, FLUORESCENCE; INFANT; INTERPHASE; MALE; METAPHASE; REPRODUCIBILITY OF RESULTS;

EID: 0036211757     PISSN: 10158146     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (15)

1. Detection of trisomy 12 and centromeric alterations in CLL by interphase- and metaphase-FISH
2. Identification of chromosome specific satellite DNA using non-isotopic in situ hybridization
3. A survey of the geneomic distribution of alpha satellite DNA on all the human chromosomes, and derivation of a new consensus sequence
4. A partial trisomy 15q due to 15:17 translocation detected by conventional cytogenetic and FISH techniques
5. A novel nuclear protein binds centromeric alpha satellite DNA
6. Application of fluorescence in situ hybridization technique in clinical genetics: Use of two alphoid repeat probes detecting the centromeres of chromosomes 13 and 21 or chromosomes 14 and 22, respectively
7. Rapid detection of human chromosome 21 aberations by in situ hybridization
8. Extreme reduction of chromosome-specific alpha-satellite array is unusually common in human chromosome 21
9. Analysis of alphoid DNA variation and kinetochore size in human chromosome 21: Evidence against pathological significance of alphoid satellite diminution
10. Interphase cytogenetics of hematological cancer: Comparasion of classical karyotyping and in situ hybridization using a panel of eleven chromosoma specific DNA probes
11. Variation in alphoid DNA sequences escape detection of aneuploidy at interphase by FISH technique
12. Potential genetic functions of tandem repeated DNA sequence blocks in human genome are based on a highly conserved cromatin folding code
13. Centromeric DNA break in a 10;16 reciprocal translocation associated with trisomy 16 cofined placental mosaicism and maternal uniparental disomy for chromosome 16
14. Nucleotide sequence heterogeneity of alpha satellite repetitive DNA: A survey of alphoid sequences from different human chromosomes
15. A degenerate alpha satellite probe, detecting a centromere deletion on chromosome 21 in an apparently normal human male, shows limitations of the use of satellite DNA probes for interphase ploidy analysis