Chronic opiate exposure in the male rat adversely affects fertility

Pharmacology Biochemistry and Behavior

Volumn 72, Issue 1-2, 2002, Pages 157-163

  Cicero, Theodore J ^a   Davis, L A ^b   LaRegina, M C ^a   Meyer, E R ^a   Schlegel, M S ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Laboratory Animal Sciences   (United States)

Author keywords

Morphine and reproduction; Opiates; Opiates and reproduction; Paternal influences; Paternal opiate administration; Reproductive function

Indexed keywords

MORPHINE; OPIATE; NARCOTIC ANALGESIC AGENT;

ANIMAL TISSUE; ARTICLE; CONCEPTION; CONTROLLED STUDY; COPULATION; FEMALE; FEMALE FERTILITY; FERTILIZATION; FETUS; FETUS OUTCOME; FETUS WEIGHT; MALE; MALE FERTILITY; MATING; NONHUMAN; PREGNANCY; PRIORITY JOURNAL; PROSTATE; PSEUDOPREGNANCY; RAT; SEMINAL VESICLE; SEXUAL BEHAVIOR; SPERMATOZOON MOTILITY; TESTIS WEIGHT; VAGINA CYTOLOGY; ANIMAL; DRUG EFFECT; FERTILITY; PHYSIOLOGY; SPRAGUE DAWLEY RAT;

ANALGESICS, OPIOID; ANIMALS; FEMALE; FERTILITY; MALE; MORPHINE; RATS; RATS, SPRAGUE-DAWLEY; SEXUAL BEHAVIOR, ANIMAL;

EID: 0036211162     PISSN: 00913057     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0091-3057(01)00751-1     Document Type: Article

References (29)

1. The effects of copulatory behavior on sperm transport and fertility in rats
2. Opioids and sexual behavior in the male rat
3. Alcohol and fetal damage
4. Ethanol-induced male infertility: Impairment of spermatozoa
5. Potential biological markers in individuals at high risk for developing alcoholism
6. On the factors involved in sperm transport through the cervix uteri of the albino rat
7. Structure of the vaginal plugs generated by normal rats and by rats with partially removed seminal vesicles
8. Effects of chronic morphine administration of the reproductive system of the male rat
9. Function of the male sex organs in heroin and methadone users
10. Influence of morphine exposure during adolescence on the sexual maturation of male rats and the development of their offspring
11. Adverse effects of paternal opiate exposure on offspring development and sensitivity to morphine-induced analgesia
12. Paternal contributions to birth defects
13. Duct system and accessory glands of the male reproductive tract
14. Effects of limited paternal exposure to xenobiotic agents on the development of progeny
15. Paternal pregestational opiate exposure in male mice: Neuroendocrine deficits in their offspring
16. Paternal drug exposure: Effects on reproduction and progeny
17. Fundamentals of male reproductive toxicity testing
18. Systematic interrelationship of mating, vaginal plug position and sperm transport in the rat
19. A review of the neurobehavioral deficits in children with fetal alcohol syndrome or prenatal exposure to alcohol
20. Sexual behavior of morphine-dependent and abstinent male rats
21. Human mutagens: Evidence from paternal exposure
22. The corpus luteum and its control
23. Prenatal drug exposure and child outcome. Past, present, future
24. Increased neonatal mortality in offspring of male rats treated with methadone or morphine before mating
25. Adolescent sons of alcoholics: Neuropsychological and personality characteristics
26. Specific cognitive impairments in sons of early onset alcoholics
27. Effects of repeated morphine administration on copulation and on the hypothalamic-pituitary-gonadal axis of male rats
28. Dietary two-generation reproduction study of thiabendazole in Sprague-Dawley rats