Influence of Valsartan on myocardial apoptosis in spontaneously hypertensive rats

Chinese Medical Journal

Volumn 115, Issue 3, 2002, Pages 364-366

  Ding, Xiuyun ^a   Yue, Jiachang ^b   Wang, Shiwen ^a   Gao, Xue ^a   Li, Xianfeng ^b  

^a CHINESE PLA GENERAL HOSPITAL   (China)

^b INSTITUTE OF BIOPHYSICS   (China)

Author keywords

Apoptosis; Cardiac hypertrophy; Heart failure; TUNEL; Valsartan

Indexed keywords

PLACEBO; VALSARTAN;

AGE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BLOOD PRESSURE MEASUREMENT; BODY WEIGHT; CELL DENSITY; CELL NUCLEUS; CLINICAL OBSERVATION; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; ESSENTIAL HYPERTENSION; HEART FAILURE; HEART HYPERTROPHY; HEART MUSCLE CELL; HEART WEIGHT; INHIBITION KINETICS; NEWBORN; NICK END LABELING; NONHUMAN; RAT; RAT STRAIN; SPONTANEOUSLY HYPERTENSIVE RAT; SYSTOLIC BLOOD PRESSURE;

ANIMALS; ANTIHYPERTENSIVE AGENTS; APOPTOSIS; CARDIOMEGALY; HYPERTENSION; MYOCARDIUM; RATS; RATS, INBRED SHR; RATS, WISTAR; TETRAZOLES; VALINE;

EID: 0036208583     PISSN: 03666999     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (5)

1. Brain cell apoptosis after cerebral hypoxia-ischemia in neonatal rat
2. Apoptosis cell death in heart failure
3. Tumor necrosis factor in myocardial hypertrophy and ischemia: An anti-apoptotic perspersive
4. In vivo study of AT1 and AT2 angiotensin receptors in apoptosis in rat blood vessels
5. Stretch-mediated release of angiotensin II induces myocyte apoptosis by activating p53 that enhances the local renin-angiotensin system and decreases the Bcl-2-to-Bax protein ratio in the cell