Relationship between the platelet activating factor acetylhydrolase gene and intractability of ulcerative colitis

Diseases of the Colon and Rectum

Volumn 45, Issue 3, 2002, Pages 389-393

  Nakamura, Toshio ^a   Sakaguchi, Takanori ^a   Unno, Naoki ^a   Sugatani, Junko ^b   Miwa, Masao ^b   Nakamura, Satoshi ^a  

^a HAMAMATSU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b UNIVERSITY OF SHIZUOKA   (Japan)

Author keywords

Platelet activating factor acetylhydrolase; Ulcerative colitis

Indexed keywords

1 ALKYL 2 ACETYLGLYCEROPHOSPHOCHOLINE ESTERASE; GENOMIC DNA;

ADULT; ALLELE; ARTICLE; COLITIS; CONTROLLED STUDY; FEMALE; GENE FREQUENCY; GENE MUTATION; GENOTYPE; HUMAN; MAJOR CLINICAL STUDY; MALE; ULCERATIVE COLITIS;

ADULT; ANTI-INFLAMMATORY AGENTS; COLITIS, ULCERATIVE; DRUG RESISTANCE; FEMALE; GENOTYPE; HUMANS; HYDROLASES; MALE; MIDDLE AGED; MUTATION; PLATELET ACTIVATING FACTOR; POLYMERASE CHAIN REACTION; SEVERITY OF ILLNESS INDEX; STEROIDS;

EID: 0036208321     PISSN: 00123706     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10350-004-6188-y     Document Type: Article

References (24)

1. Release of platelet-activating factor (PAF) and histamine. II. The cellular origin of human PAF monocytes, polymorphonuclear neutrophils and basophils
2. Bowel necrosis induced by tumor necrosis factor in rats is mediated by platelet-activating factor
3. Platelet-activating factor produces shock, in vivo complement activation, and tissue injury in mice
4. Role of platelet-activating factor in ulcerative colitis: Enhanced production during active disease and inhibition by sulfasalazine and prednisolone
5. Characterization of serum platelet-activating factor (PAF) acetylhydrolase: Correlation between deficiency of serum PAF acetylhydrolase and respiratory symptoms in asthmatic children
6. Platelet-activating factor acetylhydrolase deficiency: A missense mutation near the active site of an anti-inflammatory phospholipase
7. Deficiency of platelet-activating factor acetylhydrolase is a severity factor for asthma
8. Intensive intravenous regimen for severe attacks of ulcerative colitis
9. Distinct associations of HLA class II genes with inflammatory bowel disease
10. Molecularly defined HLA-DR2 alleles in ulcerative colitis and an antineutrophil cytoplasmic antibody-positive subgroup
11. Significance of interleukin-1beta and interleukin-1 receptor antagonist genetic polymorphism in inflammatory bowel diseases
12. Novel genetic association between ulcerative colitis and the anti-inflammatory cytokine interleukin-1 receptor antagonist
13. Tumor necrosis factor microsatellites define a Crohn's disease-associated haplotype on chromosome 6
14. Evidence for platelet-activating factor as a mediator of endotoxin-induced gastrointestinal damage in the rat: Effects of three platelet-activating factor antagonists
15. Platelet-activating factor-induced mucosal dysfunction: Role of oxidants and granulocytes
16. Release of platelet-activating factor (PAF) and accelerated healing induced by a PAF antagonist in an animal model of chronic colitis
17. Release of platelet-activating factor in systemic lupus erythematosus
18. Plasma degradation of platelet-activating factor in severely ill patients with clinical sepsis
19. Hypoxia causes ischemic bowel necrosis in rats: The role of platelet-activating factor (PAF-acether)
20. Platelet-activating factor acetylhydrolase gene mutation in Japanese nephrotic children
21. The central role of PAF in necrotizing enterocolitis development
22. The hormonal regulation of platelet-activating factor acetylhydrolase activity in plasma
23. Hormonal regulation of platelet-activating factor-acetyltransferase activity in rat tissues
24. Raised concentrations of platelet activating factor in colonic mucosa of Crohn's disease patients