Influence of physicochemical properties on pharmacokinetics of non-viral vectors for gene delivery

Journal of Drug Targeting

Volumn 10, Issue 2, 2002, Pages 99-104

  Takakura, Yoshinobu ^a   Nishikawa, Makiya ^a   Yamashita, Fumiyoshi ^a   Hashida, Mitsuru ^a  

^a KYOTO UNIVERSITY   (Japan)

Author keywords

In vivo gene delivery; Lipoplex; Pharmacokinetics; Physicochemical properties; Polyplex; Receptor mediated endocytosis

Indexed keywords

CATION; CELL RECEPTOR; CHOLESTEN 5 YLOXY N [4 [(1 IMINO 2 BETA THIOGALACTOSYLETHYL)AMINO]BUTYL] FORMAMIDE; CHOLESTEN 5 YLOXY N [4 [(1 IMINO 2 BETA THIOMANNOSYL ETHYL)AMINO]BUTYL]FORMAMIDE; LIPOSOME; N [1 (2,3 DIOLEYLOXY)PROPYL] N,N,N TRIMETHYLAMMONIUM CHLORIDE; PHOSPHORUS 32; PLASMID DNA; POLYGALACTURONIC ACID; POLYMER; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DNA VECTOR; DRUG DESIGN; DRUG TARGETING; ENDOCYTOSIS; IN VIVO STUDY; LIVER CELL; MOLECULAR SIZE; MOUSE; NONHUMAN; NONVIRAL GENE DELIVERY SYSTEM; NONVIRAL GENE THERAPY; PHYSICAL CHEMISTRY; PRIORITY JOURNAL;

ANIMALS; CHEMISTRY, PHYSICAL; DNA, BACTERIAL; DRUG DELIVERY SYSTEMS; GENE THERAPY; GENETIC VECTORS; HUMANS; LIPOSOMES;

EID: 0036204833     PISSN: 1061186X     EISSN: None     Source Type: Journal    
DOI: 10.1080/10611860290016694     Document Type: Article

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