Involvement of nitric oxide in the ocular hypotensive action of nipradilol

Current Eye Research

Volumn 23, Issue 5, 2001, Pages 346-351

  Sugiyama, Tetsuya ^a   Kida, Teruyo ^a   Mizuno, Ken ^a   Kojima, Shota ^a   Ikeda, Tsunehiko ^a  

^a OSAKA MEDICAL COLLEGE   (Japan)

Author keywords

Intraocular pressure; Nipradilol; Nitric oxide; Outflow facility; Uveoscleral outflow

Indexed keywords

ANTIHYPERTENSIVE AGENT; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; DENITRONIPRADILOL; NIPRADILOL; NITRIC OXIDE; NITRIC OXIDE TRAPPING AGENT; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANTERIOR EYE CHAMBER; AQUEOUS HUMOR; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; DRUG INHIBITION; DRUG MECHANISM; EYE BLOOD FLOW; INTRAOCULAR HYPOTENSION; INTRAOCULAR PRESSURE; MALE; NONHUMAN; PERFUSION; PRIORITY JOURNAL; RABBIT; RECEPTOR BLOCKING; SCLERA; TIME;

ADMINISTRATION, TOPICAL; ADRENERGIC ALPHA-ANTAGONISTS; ADRENERGIC BETA-ANTAGONISTS; ANIMALS; ANTERIOR CHAMBER; ANTIHYPERTENSIVE AGENTS; AQUEOUS HUMOR; BENZOATES; IMIDAZOLES; INTRAOCULAR PRESSURE; NITRIC OXIDE; PROPANOLAMINES; RABBITS; SCLERA; UVEA; VASODILATOR AGENTS;

EID: 0036202896     PISSN: 02713683     EISSN: None     Source Type: Journal    
DOI: 10.1076/ceyr.23.5.346.5438     Document Type: Article

References (23)

1. Mechanism of the pathogenesis of glutamate neurotoxicity in retinal ischemia
2. Protective effect of nitric oxide on ischemic retina
3. Increased intraocular pressure following topical azide or nitroprusside
4. Nitrovasodilators as a new class of ocular hypotensive agents
5. Effect of a nitric oxide donor on intraocular pressure
6. Vasoactive and β-adrenoceptor blocking properties of 3,4-dihydro-8-(2-hydroxy-3-isopropyl-amino)propoxy-3-nitroxy-2H-1-benzopyran (K-351), a new antihypertensive agent
7. Canine retinal arterial and arteriolar dilatation induced by Nipradilol, a possible glaucoma therapeutic
8. Ocular hypotensive effects of nipradirol ophthalmic solution, KT-210, in rabbits
9. Phase III comparative clinical study on KT-210 in patients with primary open-angle glaucoma and ocular hypertension-Multicenter cooperative between-group comparative double-blind clinical trial with 0.5% timolol maleate ophthalmic solution
10. Effects of topical nipradilol, a β-blocking agent with α-blocking and nitroglycerin-like activities, on aqueous humor dynamics and fundus circulation
11. Simultaneous measurement of changing intraocular pressure and outflow facility in velvet monkey by constant pressure infusion
12. Effects of endothelin-1 on intraocular pressure and aqueous humor dynamics in the rabbit eye
13. Uveoscleral outflow following cyclodialysis in the monkey eye using a fluorescent tracer
14. 2 on the aqueous humor dynamics in rabbits
15. 2-adrenoceptor agonists on intraocular pressure in the conscious rabbit
16. Effects of ocular hypotensive agents on prostaglandin-mediated elevation of interocular pressure
17. Effects of intraocular pressure change on movement of FITC-dextran across vitreous-aqueous interface
18. Effect of bunazosin hydrochloride on intraocular pressure and aqueous humor dynamics in normotensive human eyes
19. Mechanisms for ocular hypotensive effects of bunazosin hydrochlorides in albino rabbits
20. Up-regulation of endothelial nitric oxide synthase through β2-adrenergic receptor -the role of a β-blocker with NO-releasing action
21. Nipradilol: A novel topical alpha- and beta-adrenergic antagonist which produces nitric oxide
22. Characterization of ciliary muscle relaxation induced by various agents in cats
23. Effect of nipradilol ophthalmic solition (KT-210) on the aqueous humor dynamics in rabbit eyes