Adenovirus-mediated TGF-β1 gene transfer to human degenerative lumbar intervertebral disc cells

Chinese Medical Journal

Volumn 115, Issue 3, 2002, Pages 409-412

  Xiao, Yuanhong ^a   Liu, Guilin ^a  

^a CHINESE PLA GENERAL HOSPITAL   (China)

Author keywords

Adenovirus; Degenerative disc cell; Gene therapy; Growth factor; Lumbar intervertebral disc

Indexed keywords

ADENOVIRUS VECTOR; COMPLEMENTARY DNA; GREEN FLUORESCENT PROTEIN; TRANSFORMING GROWTH FACTOR BETA1;

ADULT; ARTICLE; CELL CULTURE; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOMEGALOVIRUS; DNA MODIFICATION; FEMALE; FLUORESCENCE ANALYSIS; GENE CONSTRUCT; GENE DELIVERY SYSTEM; GENE EXPRESSION; GENETIC TRANSDUCTION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; INTERVERTEBRAL DISK DEGENERATION; INTERVERTEBRAL DISKECTOMY; LUMBAR DISK; MALE; MARKER GENE; NUCLEUS PULPOSUS; PROTEIN EXPRESSION; TRANSGENE;

ADENOVIRIDAE; ADULT; FEMALE; GENE TRANSFER TECHNIQUES; HUMANS; INTERVERTEBRAL DISK; LUMBAR VERTEBRAE; MALE; MIDDLE AGED; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA1;

EID: 0036202307     PISSN: 03666999     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (10)

1. Viscoelastic properties of intervertebral disc cells
2. Identification of heterogenous cell populations in normal human intervertebral disc
3. Type-II collagen gene expression is transiently upregulated in experimentally induced degeneration of rabbit intervertebral disc
4. Stimulation of mature canine intervertebral disc by growth factors
5. 1) on gene expression of collagen type II in human intervertebral discs
6. Effect of growth factors in vivo
7. Adenovirus-mediated gene transfer to nucleus pulposus cells. Implications for the treatment of intervertebral disc degeneration
8. Human intervertebral disc cells are genetically modifiable by adenovirus-mediated gene transfer
9. Human adenovirus vectors for gene transfer into mammalian cells
10. Transfer of therapeutic genes to human chondrocyte like cells of lumbar disc prolapse