Species-restricted antibody response against a DNA-construct coding for aspartic proteinase from Schistosoma japonicum

Parasitology Research

Volumn 88, Issue 4, 2002, Pages 368-375

  Chlichlia, K ^a   Bahgat, M ^a   Schirrmacher, V ^b   Ruppel, A ^a  

^a UNIVERSITY OF HEIDELBERG   (Germany)

^b GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ASPARTIC PROTEINASE; CATHEPSIN D; DNA VACCINE; PARASITE ANTIGEN;

ANIMAL CELL; ANIMAL TISSUE; ANTIBODY RESPONSE; ARTICLE; CONTROLLED STUDY; CROSS REACTION; ENHANCER REGION; EXPRESSION VECTOR; FEMALE; FROZEN SECTION; GENETIC CODE; HOMOGENATE; MOLECULAR CLONING; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; SCHISTOSOMA JAPONICUM; SCHISTOSOMA MANSONI; SPECIES DIFFERENCE; VACCINATION;

ANIMALS; ANTIBODIES, HELMINTH; CATHEPSIN D; CERCOPITHECUS AETHIOPS; COS CELLS; CROSS REACTIONS; DNA, COMPLEMENTARY; DNA, HELMINTH; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE, DIRECT; HUMANS; MICE; MICE, INBRED STRAINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SCHISTOSOMA JAPONICUM; SPECIES SPECIFICITY; TRANSFECTION; VACCINATION; VACCINES, DNA;

ANIMALIA; CUCUMBER MOSAIC VIRUS; MAMMALIA; PINNA; SCHISTOSOMA; SCHISTOSOMA JAPONICUM; SCHISTOSOMA MANSONI; TREMATODA; VECTORS;

EID: 0036200367     PISSN: 09320113     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00436-001-0547-6     Document Type: Article

References (35)

1. DNA vaccines: Technology and application as anti-parasite and anti-microbial agents
2. Cloning and characterization of the Schistosoma japonicum aspartic proteinase involved in hemoglobin degradation
3. Schistosoma japonicum: Ultrastructural localization of a haemoglobinase using mercury labelled pepstatin
4. Schistosoma japonicum: Immunocytochemistry of adults using heterologous anti-serum to bovine cathepsin D
5. Schistosoma japonicum: Immunoinhibitory studies on haemoglobin digestion using heterologous antiserum to bovine cathepsin D
6. Proteolytic degradation of host hemoglobin by schistosomes
7. Proteolysis of human hemoglobin by schistosome cathepsin D
8. The antibody repertoire in infection and vaccination with Dictyocaulus viviparus: Heterogeneity in infected cattle and genetic control in guinea pigs
9. Cathepsin B-like activity predominates over cathepsin L-like activity in adult Schistosoma mansoni and S. japonicum
10. Schistosoma japonicum and S. mansoni: Effect of cyclosporin A on aspartic and cysteine hemoglobinolytic activities
11. Schistosomiasis: Forty years' war on the worm
12. High-efficiency transformation of mammalian cells by plasmid DNA
13. Digestion of haemoglobin by schistosomes: 35 Years on
14. Superiority of the ear pinna over muscle tissue as site for DNA vaccination
15. Persistence of dormant tumor cells in the bone marrow of tumor cell vaccinated mice correlates with long-term immunological protection
16. Primary structures of Sm31/32 diagnostic proteins of Schistosoma mansoni and their identification as proteases
17. A semi-empirical method for prediction of antigenic determinants on protein antigens
18. Point mutations define a sequence flanking the AUG initiator codon that modulates translation by eukaryotic ribosomes
19. Cleavage of structural proteins during the assembly of the head of bacteriophage T4
20. The search for a vaccine against schistosomiasis - A difficult path but an achievable goal
21. cDNA sequences of Schistosoma japonicum coding for two cathepsin B-like proteins and Sj32
22. Naked DNA - The poor man's gene therapy?
23. Immunoblot analysis of Schistosoma mansoni antigens with sera of schistosomiasis patients: Diagnostic potential of an adult schistosome polypeptide
24. Sera of Schistosoma japonicum-infected patients cross-react with diagnostic 31/32 kD proteins of S. mansoni
25. Schistosoma mansoni and S. japonicum: Comparison of levels of ultraviolet irradiation for vaccination of mice with cercariae
26. Intra-pinna anti-tumor vaccination with self-replicating infectious RNA or with DNA encoding a model tumor antigen and a cytokine
27. Schistosoma japonicum: An ultraviolet-attenuated vaccine applicable in the field for water buffaloes
28. Neutralization of the activity of a Fasciola hepatica cathepsin L proteinase by anti-cathepsin L antibodies
29. Proteinases and associated genes of parasitic helminths
30. Vaccine efficacy of recombinant cathepsin D aspartic protease from Schistosoma japonicum
31. Cysteine protease inhibitors block schistosome hemoglobin degradation in vitro and decrease worm burden and egg production in vivo
32. DNA vaccination strategies against infectious diseases
33. Strategies for a schistosome vaccine: Can we manipulate the immune response effectively?
34. Schistosomes express two forms of cathepsin D
35. Protective immunity induced by the full-length cDNA encoding paramyosin of Chinese Schistosoma japonicum