Loss of luteinizing hormone surges induced by chronic estradiol is associated with decreased activation of gonadotropin-releasing hormone neurons

Biology of Reproduction

Volumn 66, Issue 4, 2002, Pages 1104-1110

  Tsai, Houng W ^a   Legan, Sandra J ^a  

^a UNIVERSITY OF KENTUCKY   (United States)

Author keywords

Aging; Estradiol; GnRH; Hypothalamus; LH; Progesterone

Indexed keywords

ESTRADIOL; GONADORELIN; LUTEINIZING HORMONE; PROGESTERONE; STEROID;

ANIMAL TISSUE; ARTICLE; BLOOD SAMPLING; CONTROLLED STUDY; FEMALE; GENE LOCATION; HORMONAL REGULATION; HYPOTHALAMUS; IMMUNOCYTOCHEMISTRY; LONG TERM EXPOSURE; LUTEINIZING HORMONE RELEASE; NONHUMAN; ONCOGENE C FOS; OVARIECTOMY; PRIORITY JOURNAL; RAT;

ANIMALIA;

EID: 0036196592     PISSN: 00063363     EISSN: None     Source Type: Journal    
DOI: 10.1095/biolreprod66.4.1104     Document Type: Article

References (55)

1. Effects of antibodies to 17β-estradiol and progesterone on the estrous cycle of the rat
2. A neurogenic timing factor in control of the ovulatory discharge of luteinizing hormone in the cyclic rat
3. A 24-hour periodicity in the "LH-release apparatus" of female rats, disclosed by barbiturate sedation
4. Extinction of the estrogen-induced daily signal for LH release in the rat: A role for the proestrous surge of progesterone
5. Postnatal morphological changes in rat LHRH neurons correlated with sexual maturation
6. A developmental study of the quantitative distribution of LHRH neurons within the central nervous system of postnatal male and female rats
7. Gonadotropin releasing hormone (GnRH)
8. Luteinizing hormone-releasing hormone neurons express Fos protein during the proestrous surge of luteinizing hormone
9. Progesterone enhances the surge of luteinizing hormone by increasing the activation of luteinizing hormone-releasing hormone neurons
10. Luteinizing hormone-releasing hormone neurons express c-fos antigen after steroid activation
11. Characterization of the LH surge in middle-aged female rats
12. Luteinizing hormone regulation and sexual behavior in middle-aged female rats
13. Alterations in proestrous LH, FSH, and prolactin surges in middle-aged rats
14. Alterations in ovarian steroid and gonadotrophin secretion preceding the cessation of regular oestrous cycles in ageing female rats
15. Relation of neuroendocrine system to loss of reproductive function in aging rats
16. Chronological changes in sex steroid, gonadotropin and prolactin secretion in aging female rats displaying different reproductive states
17. Differential patterns of gonadotropin responses to ovarian steroids and to LH-releasing hormone between constant-estrous and pseudopregnant states in aging rats
18. Neuroendocrine control of luteinizing hormone secretion and reproductive function in spontaneously persistent-estrous aging rats
19. Gonadotropin surges elicited by progesterone after estradiol (E2)-priming, but not by E2 alone, in middle-aged, acyclic female rats exhibiting early persistent estrus (PE)
20. Induction of LH surges by progesterone in early persistent-estrous rats is mediated by activation of hypothalamic LHRH neurons
21. Relationship between circulating estrogens and the central mechanisms by which ovarian steroids stimulate luteinizing hormone secretion in aged and young female rats
22. A daily signal for the LH surge in the rat
23. Circadian rhythm of luteinizing hormone secretion in the ovariectomized rat implanted with oestradiol
24. Inhibition of prolactin secretion delays extinction of circadian LH surges in ovariectomized rats bearing estradiol implants
25. Chronic elevation of estradiol in young ovariectomized rats causes aging-like loss of steroid-induced luteinizing hormone surges
26. Role of estrogen as initiator of daily LH surges in the ovariectomized rat
27. A rapid and simple procedure for chronic cannulation of the rat jugular vein
28. Use of cryoprotectant to maintain long-term peptide immunoreactivity and tissue morphology
29. Detecting steroidal effects on immediate early gene expression in the hypothalamus
30. Suppression of tonic luteinizing hormone secretion and norepinephrine release near the GnRH neurons by estradiol in ovariectomized rats
31. Ovariectomy of young adult rats has a sparing effect on the ability of aged rats to release luteinizing hormone
32. Decline in immediate early gene expression in gonadotropin-releasing hormone neurons during proestrus in regularly cycling, middle-aged rats
33. A reduced proportion of luteinizing hormone (LH)-releasing hormone neurons express fos protein during the preovulatory or steroid-induced LH surge in middle-aged rats
34. 1-adrenergic receptor blockade blocks LH secretion but not LHRH cFos activation
35. The role of catecholamines in the regulation of pituitary luteinizing hormone and follicle-stimulating hormone secretion
36. Neural regulation of luteinizing hormone secretion in the rat
37. Neural circuitry involved in the control of LHRH secretion: A model for preovulatory LH release
38. Multimodal influence of estrogen upon gonadotropinreleasing hormone neurons
39. Subgroups of luteinizing hormone-releasing hormone perikarya defined by computer analyses in the basal forebrain of intact female rats
40. Dual label in situ hybridization studies provide evidence that luteinizing hormone-releasing hormone neurons do not synthesize messenger ribonucleic acid for μ, κ, δ, or opiate receptors
41. Identification of glutamate receptor subtype mRNAs in gonadotropin-releasing hormone neurons in rat brain
42. IB adrenergic receptor protein in gonadotropin releasing hormone neurons of the female rat
43. Gender-specific apposition between vasoactive intestinal peptide-containing axons and gonadotropin-releasing hormone-producing neurons in the rat
44. Morphological evidence for direct interaction between arcuate nucleus neuropeptide Y (NPY) neurons and gonadotropin-releasing hormone neurons and the possible involvement of NPY Y1 receptors
45. Response of the adult rat to orchidectomy and ovariectomy as determined by LH radioimmunoassay
46. Analysis of initial and delayed effects of orchidectomy and ovariectomy on pituitary and serum LH levels in adult and immature rats
47. Acute and long-term changes in central and pituitary mechanisms regulating pulsatile luteinizing hormone secretion after ovariectomy in the rat
48. Inhibitory effects of estrogen and progesterone on several parameters of pulsatile LH release in the ovariectomized rat
49. The influence of progesterone and estradiol on the acute changes in pulsatile luteinizing hormone release induced by ovariectomy on diestrus day 1 in the rat
50. Luteinizing hormone releasing factor in pituitary stalk plasma from long-term ovariectomized rats: Effects of steroids
51. Effect of ovariectomy and adrenalectomy on luteinizing hormone-releasing hormone in pituitary stalk blood from female rats
52. Corticotropin-releasing factor decreases plasma luteinizing hormone levels in female rats by inhibiting gonadotropin-releasing hormone release into hypophysial-portal circulation
53. Luteinizing hormone-releasing hormone release during the rat estrous cycle and after ovariectomy as estimated with push-pull cannulae
54. Ovarian and steroidal influences on neuroendocrine aging processes in female rodents
55. Reproductive aging and neuroendocrine function