Ionomycin-induced neutrophil NADPH oxidase activity is selectively inhibited by the serine protease inhibitor diisopropyl fluorophosphate

Antioxidants and Redox Signaling

Volumn 4, Issue 1, 2002, Pages 17-25

  Dahlgren, Claes ^a   Karlsson, Anna ^a  

^a UNIVERSITY OF GOTHENBURG   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

DYFLOS; FORMYLMETHIONYLLEUCYLPHENYLALANINE; IONOMYCIN; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; SERINE PROTEINASE INHIBITOR;

ADULT; ARTICLE; CELL GRANULE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; HUMAN; HUMAN CELL; INFLAMMATION; LEUKOCYTE ACTIVATION; NORMAL HUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

EID: 0036196235     PISSN: 15230864     EISSN: None     Source Type: Journal    
DOI: 10.1089/152308602753625816     Document Type: Article

References (27)

1. Prevention of degradation of human polymorphonuclear leukocyte proteins by diisopropylfluorophosphate
2. 2+ influx across the plasma membrane of human neutrophils
3. Regulation of cell function by Rho family GTPases
4. Granules of the human neutrophilic polymorphonuclear leukocyte
5. Subcellular localization of the b-cytochrome component of the human neutrophil microbicidal oxidase: Translocation during activation
6. Separation of leucocytes: Improved cell purity by fine adjustments of gradient medium density and osmolality
7. Proinflammatory activity of a cecropin-like antibacterial peptide from Helicobacter pylori
8. 2 specifically activates netrophils through FPRL1/LXA4R and is an agonist for the orphan monocyte-expressed chemoattractant receptor FPRL2
9. Difference in extracellular radical release after chemotactic factor and calcium ionophore activation of the oxygen radical-generating system in human neutrophils
10. The calcium ionophore ionomycin can prime, but not activate, the reactive oxygen generating system in differentiated HL-60 cells
11. Respiratory burst in human neutrophils
12. Activation of the oxygen-radical-generating system in granules of intact human neutrophils by a calcium ionophore (ionomycin)
13. 3 receptor antagonists
14. Skin chamber technique for study of in vivo exudated human neutrophils
15. 2+ concentrations are essential and synergize with a kinetically distinct second signal
16. Function and regulation of chemoattractant receptors
17. Different subcellular localization of cytochrome b and the dormant NADPH-oxidase in neutrophils and macrophages: Effect on the production of reactive oxygen species during phagocytosis
18. Assembly and activation of the neutrophil NADPH oxidase in granule membranes
19. The two-step conversion of big endothelin 1 to endothelin 1 and degradation of endothelin 1 by subcellular fractions from human polymorphonuclear leukocytes
20. Desensitization of formyl peptide receptors is abolished in calcium ionophore-primed neutrophils: An association of the ligand-receptor complex to the cytoskeleton is not required for a rapid termination of the NADPH-oxidase response
21. Caspases: More than just killers?
22. Phagocytosis following translocation of the neutrophil b-cytochrome from the specific granule to the plasma membrane is associated with an increased leakage of reactive oxygen species
23. Neutrophil control of formylmethionyl-leucyl-phenylalanine induced mobilization of secretory vesicles and NADPH-oxidase activation: Effect of an association of the ligand-receptor complex to the cytoskeleton
24. Phorbol myristate acetate-induced NADPH oxidase activity in human neutrophils: Only half the story has been told
25. A rise in ionized calcium activates the neutrophil NADPH-oxidase but is not sufficient to directly translocate cytosolic p 47phox or p67phox to b cytochrome containing membranes
26. 2+-induced exocytosis in individual human neutrophils: High- and low-affinity granule populations and submaximal responses
27. Mobilization of granules and secretory vesicles during in vivo exudation of human neutrophils