Azelastine and suplatast shorten the distribution half-life of IgE in rats

Mediators of Inflammation

Volumn 11, Issue 1, 2002, Pages 61-64

  Hanashiro, Kazuhiko ^a   Tokeshi, Yoshihiro ^a   Nakasone, Toshiyuki ^a   Sunagawa, Masanori ^a   Nakamura, Mariko ^a   Kosugi, Tadayoshi ^a  

^a UNIVERSITY OF THE RYUKYUS   (Japan)

Author keywords

Anti allergic drugs; IgE; Pharmacokinetics; Rat; Turnover

Indexed keywords

2,4 DINITROPHENOL; AZELASTINE; IMMUNOGLOBULIN E; SUPLATAST TOSYLATE;

ALLERGY; ANIMAL EXPERIMENT; ARTICLE; CIRCULATION; CONTROLLED STUDY; DRUG EFFECT; ENZYME LINKED IMMUNOSORBENT ASSAY; HALF LIFE TIME; IMMUNOGLOBULIN BLOOD LEVEL; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; SENSITIZATION;

ANIMALS; ANTI-ALLERGIC AGENTS; ARYLSULFONATES; ENZYME-LINKED IMMUNOSORBENT ASSAY; HALF-LIFE; IMMUNOGLOBULIN E; MALE; PHTHALAZINES; RATS; RATS, WISTAR; SULFONIUM COMPOUNDS;

ANIMALIA; RATTUS NORVEGICUS;

EID: 0036195913     PISSN: 09629351     EISSN: None     Source Type: Journal    
DOI: 10.1080/09629350210310     Document Type: Article

References (6)

1. Analysis of IgE turnover in non-sensitized and sensitized rats
2. Production of monoclonal dinitrophenyl-specific rat IgE and establishment of an IgE-capture ELISA for estimating the concentration of rat IgE antibodies to dinitrophenyl-Ascaris suum
3. Half-lives of two types of rat homocytotropic antibodies in circulation and in the skin
4. Effect of IPD-1151T (Suplatast Tosilate) on airway hyperresponsiveness in mice
5. Inhibitory effect of azelastine hydrochloride and suplatast tosilate on airway responses in sensitized rats following exposure to antigen
6. The inhibitory actions of azelastine hydrochloride on the early and late bronchoconstrictor responses to inhaled allergen in atopic asthma