Granulocyte colony-stimulating factor exacerbates the acute lung injury and pulmonary fibrosis induced by intratracheal administration of bleomycin in rats

Experimental and Toxicologic Pathology

Volumn 53, Issue 6, 2002, Pages 501-510

  Adachi, Kenji ^a   Suzuki, Masami ^a   Sugimoto, Tetsurou ^a   Suzuki, Shigeo ^a   Niki, Rikio ^c   Oyama, Atsushi ^d   Uetsuka, Koji ^b   Nakamaya, Hiroyuki ^b   Doi, Kunio ^b  

^a CHUGAI PHARMACEUTICAL CO LTD   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

^c SLA Research Inc   (Japan)

^d AICHI PREFECTURAL UNIVERSITY   (Japan)

Author keywords

Bleomycin; Diffuse alveolar damage; Granulocyte colony stimulating factor; Neutrophil; Pulmonary fibrosis

Indexed keywords

BLEOMYCIN; GRANULOCYTE COLONY STIMULATING FACTOR; SODIUM CHLORIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL ACTIVATION; CELL COUNT; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; HISTOPATHOLOGY; LONG TERM CARE; LUNG FIBROSIS; LUNG INJURY; LUNG PARENCHYMA; LUNG TOXICITY; MALE; NEUTROPHIL CHEMOTAXIS; NONHUMAN; RAT;

ANIMALIA;

EID: 0036195348     PISSN: 09402993     EISSN: None     Source Type: Journal    
DOI: 10.1078/0940-2993-00218     Document Type: Article

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