MICA-A5.1 allele is associated with atypical forms of celiac disease in HLA-DQ2-negative patients

Immunogenetics

Volumn 53, Issue 10-11, 2002, Pages 989-991

  Lopez Vazquez, Antonio ^a,b,c   Rodrigo, Luis ^a,b,c   Fuentes, Dolores ^a,b,c   Riestra, Sabino ^a,b,c   Bousoño, Carlos ^a,b,c   Garcia Fernandez, Sonia ^a,b,c   Martinez Borra, Jesús ^a,b,c   Gonzalez, Segundo ^a,b,c   Lopez Larrea, Carlos ^a,b,c  

^a HOSPITAL UNIVERSITARIO CENTRAL DE ASTURIAS   (Spain)

^b HOSPITAL VALLE DEL NALÓN   (Spain)

^c UNIVERSITY OF OVIEDO   (Spain)

Author keywords

Celiac disease; DQ2 negative; HLA DQ alleles; MICA alleles

Indexed keywords

HLA DQ ANTIGEN;

ABDOMINAL PAIN; ALLELE; ARTICLE; CELIAC DISEASE; CLINICAL ARTICLE; CONTROLLED STUDY; DIARRHEA; HLA SYSTEM; HUMAN; PRIORITY JOURNAL; STATISTICAL ANALYSIS;

ADULT; ALLELES; CELIAC DISEASE; CHILD; DIGESTIVE SYSTEM; GENETIC PREDISPOSITION TO DISEASE; HISTOCOMPATIBILITY ANTIGENS CLASS I; HLA-B ANTIGENS; HLA-DQ ANTIGENS; HUMANS;

EID: 0036193589     PISSN: 00937711     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00251-001-0413-9     Document Type: Article

References (8)

1. HLA-DR53 molecules are associated with susceptibility to celiac disease and selectively bind gliadin-derived peptides
2. Microsatellite polymorphism of the MHC class I chain-related (MIC-A and MIC-B) genes marks the risk for autoimmune Addison's disease
3. The HLA-DRB4 gene is present in half of the Spanish HLA-DQ2 negative celiac patients
4. Recognition of stress-induced MHC molecules by intestinal epithelial gamma delta T cells
5. MHC class I chain-related gene A (MICA) modulates the development of celiac disease in patients with the high-risk heterodimer DQA1 *0501/DQB1 *0201
6. HLA-DQB1 and -DQA1 typing by PCR amplification with sequence-specific primers (PCR-SSP) in 2 hours
7. The HLA-DRB4 gene does not explain genetic susceptibility in HLA-DQ2-negative patients
8. Molecular basis of celiac disease