Pharmacodynamic studies on the angiotensin II type 1 antagonists irbesartan and candesartan based on angiotensin II dose response in humans

Journal of Cardiovascular Pharmacology

Volumn 39, Issue 4, 2002, Pages 561-568

  Belz, Gustav G ^a   Butzer, Raunhild ^a   Kober, Susan ^a   Mutschler, Ernst ^a  

^a ZeKaPha GmbH   (Germany)

Author keywords

Aldosterone; Angiotensin II; Angiotensin II type 1 receptor antagonists; Candesartan; Irbesartan; Plasma renin activity; Schild regression plot

Indexed keywords

ALDOSTERONE; ANGIOTENSIN; ANGIOTENSIN 1 RECEPTOR ANTAGONIST; CANDESARTAN HEXETIL; IRBESARTAN; RADIOLIGAND;

ADRENAL GLAND; ADULT; ARTICLE; CLINICAL TRIAL; CONCENTRATION RESPONSE; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; DIASTOLIC BLOOD PRESSURE; DOSE TIME EFFECT RELATION; DOUBLE BLIND PROCEDURE; DRUG EFFECT; DRUG HALF LIFE; HUMAN; IN VIVO STUDY; KIDNEY; LINEAR REGRESSION ANALYSIS; MALE; NORMAL HUMAN; PHARMACODYNAMICS; PLASMA RENIN ACTIVITY; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL;

ADULT; ALDOSTERONE; ANGIOTENSIN II; ANTIHYPERTENSIVE AGENTS; BENZIMIDAZOLES; BIPHENYL COMPOUNDS; BLOOD PRESSURE; CROSS-OVER STUDIES; DOSE-RESPONSE RELATIONSHIP, DRUG; DOUBLE-BLIND METHOD; HALF-LIFE; HUMANS; MALE; RADIOLIGAND ASSAY; RECEPTOR, ANGIOTENSIN, TYPE 1; RECEPTORS, ANGIOTENSIN; RENIN; TETRAZOLES;

EID: 0036193504     PISSN: 01602446     EISSN: None     Source Type: Journal    
DOI: 10.1097/00005344-200204000-00012     Document Type: Article

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