Construction of a conditional allele of RSK-B/MSK2 in the mouse

Genesis

Volumn 32, Issue 2, 2002, Pages 158-160

  Casanova, Emilio ^a   Fehsenfeld, Sandra ^a   Greiner, Erich ^a   Stewart, Andrew Francis ^b   Schütz, Günther ^a  

^a GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^b EUROPEAN MOLECULAR BIOLOGY LABORATORY   (Germany)

Author keywords

ET recombination; FLPe recombinase; LoxP; MSK2; RSK B

Indexed keywords

DNA FRAGMENT; GANCICLOVIR; PROTEIN KINASE; PROTEIN KINASE RSK; UNCLASSIFIED DRUG;

ALLELE; AMINO TERMINAL SEQUENCE; ARTICLE; BACTERIAL ARTIFICIAL CHROMOSOME; CARBOXY TERMINAL SEQUENCE; DNA LIBRARY; DNA PROBE; GENE CASSETTE; GENETIC RECOMBINATION; MOLECULAR CLONING; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PHOSPHORYLATION;

ANIMALS; GENE SILENCING; INTEGRASES; MICE; MICE, TRANSGENIC; RIBOSOMAL PROTEIN S6 KINASES; RIBOSOMAL PROTEIN S6 KINASES, 90-KDA; VIRAL PROTEINS;

BACTERIA (MICROORGANISMS); RODENTIA;

EID: 0036193349     PISSN: 1526954X     EISSN: None     Source Type: Journal    
DOI: 10.1002/gene.10033     Document Type: Article

References (8)

1. Simplified generation of targeting constructs using ET recombination
2. A simple assay to determine the functionality of Cre or FLP recombination targets in genomic manipulation constructs
3. Mitogen- and stress-activated protein kinase-1 (MSK1) is directly activated by MAPK and SAPK2/p38, and may mediate activation of CREB
4. RSK-B, a novel ribosomal S6 kinase family member, is a CREB kinase under dominant control of p38alpha mitogen-activated protein kinase (p38alphaMAPK)
5. Efficient FLP recombination in mouse ES cells and oocytes
6. A Cre-transgenic mouse strain for the ubiquitous deletion of loxP-flanked gene segments including deletion in germ cells
7. Disruption of the glucocorticoid receptor gene in the nervous system results in reduced anxiety
8. A new logic for DNA engineering using recombination in Escherichia coli