Calmodulin-dependent cyclic nucleotide phosphodiesterase in an experimental rat model of cardiac ischemia-reperfusion

Canadian Journal of Physiology and Pharmacology

Volumn 80, Issue 1, 2002, Pages 59-66

  Kakkar, Rakesh ^a   Seitz, Dallas P ^a   Kanthan, Rani ^a   Rajala, Raju V S ^a   Radhi, Jasim M ^a   Wang, Xinto ^a   Pasha, Mohammed K ^a   Wang, Rui ^a   Sharma, Rajendra K ^a  

^a UNIVERSITY OF SASKATCHEWAN   (Canada)

Author keywords

Calmodulin; Calpains; Heart; Ischemia; Phosphodiesterase; Reperfusion

Indexed keywords

CALCIUM ION; CALMODULIN; CALMODULIN DEPENDENT CYCLIC NUCLEOTIDE PHOSPHODIESTERASE; CALPAIN; CALPASTATIN; CYCLIC AMP; CYCLIC NUCLEOTIDE PHOSPHODIESTERASE; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DRUG EFFECT; ENZYME ACTIVITY; ENZYME DEGRADATION; ENZYME LOCALIZATION; ENZYME PURIFICATION; ENZYME SYNTHESIS; HEART MUSCLE CELL; HEART MUSCLE ISCHEMIA; HEART MUSCLE REPERFUSION; ISOLATED HEART; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT;

3',5'-CYCLIC-NUCLEOTIDE PHOSPHODIESTERASE; ANIMALS; BLOTTING, WESTERN; CALPAIN; CATTLE; CYCLIC AMP; IMMUNOHISTOCHEMISTRY; ISCHEMIC PRECONDITIONING, MYOCARDIAL; MALE; MYOCARDIAL REPERFUSION INJURY; MYOCARDIUM; RATS; RATS, SPRAGUE-DAWLEY;

EID: 0036191739     PISSN: 00084212     EISSN: None     Source Type: Journal    
DOI: 10.1139/y02-001     Document Type: Article

References (65)

1. A calcium stimulated cysteine protease involved in isoproterenol induced cardiac hypertrophy
2. Multiple cyclic nucleotide phosphodiesterases
3. Calcium, a life and death signal
4. Proteolysis of tubulin and microtubule-associated proteins 1 and 2 by calpain I and II. Difference in sensitivity of assembled and disassembled microtubules
5. Proteinases in cardiac and skeletal muscle
6. cAMP concentrations, cAMP dependent protein kinase activity, and phospholamban in non-failing and failing myocardium
7. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
8. Calcium-activated neutral protease (calpain) system: Sturucture, function, and regulation
9. A Ca2+-activated protease possibly involved in myofibrillar protein turnover. Partial characterization of the purified enzyme
10. Differential proteolysis of the full-length form of the L-type calcium channel alpha 1 subunit by calpain
11. Cellular calcium homeostasis during ischemia; a thermodynamic approach
12. Phosphorylation of the 61-kDa calmodulin-stimulated cyclic nucleotide phosphodiesterase at serine 120 reduces its affinity for calmodulin
13. +2-dependent proteolysis
14. 2+ dependent protease system
15. 2+/calmodulin-dependent protein kinase II
16. Degradation of transcription factors, c-Jun and c-Fos, by calpain
17. Regulation of myocardial calcium channels by cyclic AMP metabolism
18. Use of avidin-biotinperoxidase complex (ABC) in immunoperoxidase techniques: A comparison between ABC and unlabeled antibody (PAP) procedures
19. Role of calpain in skeletal muscle protein degradation
20. Effects of thiol protease inhibitors on fodrin degradation during hypoxia in cultured myocytes
21. In vitro generation of an active calmodulin-independent phosphodiesterase from brain calmodulin-dependent phosphodiesterase (PDE1A2) by m-calpain
22. Calmodulin-dependent cyclic nucleotide phosphodiesterase (PDE1)
23. Decreased expression of high-molecular-weight calmodulin-binding protein and its correlation with apoptosis in ischemia-reperfused rat heart
24. Affinity chromatography of brain cyclic nucleotide phosphodiesterase using 3-(2-pyridyldithio) propionyl-substituted calmodulin linked to thiol-sepharose
25. Purification and properties of calmodulin-stimulated phosphodiesterase from mammalian brain
26. Ovine skeletal muscle multicatalytic proteinase caomplex (proteasome): Purification, characterization, and comparison of its effects on myofibrils withmu-calpain
27. Cleavage of structural proteins during the assembly of the head of bacteriophage T4
28. Immunohistochemical localization of calmodulin-dependent cyclic phosphodiesterase in the human brain
29. 2+-sensitive phosphodiesterase purified from bovine heart
30. Proteolytic processing of nuclear factor kappa B by calpain in vitro
31. Role of cyclic nucleotide phosphodiesterases in ischemic preconditioning
32. Potential arrhyth-mogenic role of cyclic adenosine monophosphate (AMP) and cytosolic calcium overload: Implications for prophylactic effects of beta-blockers in myocardial infarction and proarrhythmic effects of phosphodiesterase inhibitors
33. Purification of a cyclic nucleotide phosphodiesterase from bovine brain using blue dextran-Sepharose chromatography
34. Impairment of cGMP- and cAMP-mediated vasorelaxations in rats with chronic heart failure
35. Calmodulin-dependent cyclic nucleotide phosphodiesterases in the immature rat testis
36. Myristoyl-CoA: Protein N-myristoyltransferase from bovine cardiac muscle: Molecular cloning, kinetic analysis, and in vitro proteolytic cleavage by m-calpain
37. Testis-specific calmodulin-dependent phosphodiesterase. A distinct high affinity cAMP isoenzyme immunologically related to brain calmodulin-dependent cGMP phosphodiesterase
38. Effect of ischemic preconditioning of the myocardium on cAMP
39. Proteolytic cleavage of alpha-actinin by calpain in T cells stimulated with anti-CD3 monoclonal antibody
40. Phosphorylation and characterization of bovine heart calmodulin-dependent phosphodiesterase
41. 2+/calmodulin-dependent cyclic nucleotide phosphodiesterase (PDE1)
42. 2+-dependent modulator protein
43. Differential regulation of bovin brain calmodulin-dependent cyclic nucleotide phosphodiesterase isoenzymes by cyclic AMP-dependent protein kinase and calmodulin-dependent phosphatase
44. Purification and characterization of bovine lung calmodulin-dependent cyclic nucleotide phosphodiesterase. An enzyme containing calmodulin as a subunit
45. 2+-dependent phosphorylation and dephosphorylation of 63-kDa subunit-containing bovine brain calmodulin-stimulated cyclic nucleotide phosphodiesterase isozyme
46. Purification and properties of bovine brain calmodulin-dependent cyclic nucleotide phosphodiesterase
47. Demonstration of bovine brain calmodulin-dependent cyclic nucleotide phosphodiesterase isozymes by monoclonal antibodies
48. Calmodulin-dependent cyclic nucleotide phosphodiesterase from bovine eye: High calmodulin affinity isozyme immunologically related to the brain 60-kDa isozyme
49. 2+-calmodulin-stimulated cyclic GMP phosphodiesterase from bovine brain
50. Structure and physiological functions of ubiquitous and tissue-specific calpain species. Muscle-specific calpain, p94, interacts with connectin/titin
51. Structure and physiological function of calpains
52. Regulation of calcium slow channels of heart by cyclic nucleotides and effects of ischemia
53. Mechanical abnormalities in the rat ischemic heart failure model which lie downstream to cAMP production
54. 2+-dependent proteinase from bovine cardiac muscle
55. Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: Procedure and some applications
56. Calcium-activated neutral protease from bovine ventricular muscle: Isolation and some of its properties
57. Purification and kinetic properties of two soluble forms of calmodulin-dependent cyclic nucleotide phosphodiesterase from rat pancreas
58. Calpain inhibitors, but not caspase inhibitors, prevent actin proteolysis and DNA fragmentation during apoptosis
59. Calmodulin-binding proteins as calpain substrates
60. Calmodulin-stimulated cyclic nucleotide phosphodiesterase
61. Novel cardiac protective effects of urea: From shark to rat
62. Degradation of myofibrillar proteins by extractable lysosomal enzymes and m-calpain, and the effects of zinc chloride
63. Recent advances in cardiac beta(2)-adrenergic signal transduction
64. Calpain is implicated in rat myocardial injury after ischemia or reperfusion
65. Purification and characterization of bovine brain calmodulin-dependent protein kinase II. The significance of autophosphorylation in the regulation of 63 kDa calmodulin-dependent cyclic nucleotide phospho-diesterase isozyme