Resistance of a VEGF-producing tumor to anti-VEGF antibody: Unimpeded growth of human rhabdoid tumor xenografts

Journal of Pediatric Surgery

Volumn 37, Issue 3, 2002, Pages 528-532

  Soffer, Samuel Z ^a,b   Kim, Eugene ^a,b   Huang, Jianzhong ^a,b   McCrudden, Kimberly ^a,b   Yokoi, Akiko ^a,b   Moore, James T ^a,b   Manley, Christina ^a,b   O'Toole, Kathleen ^a,b   Middlesworth, William ^a,b   Stolar, Charles ^a,b   Yamashiro, Darrell J ^a,b   Kandel, Jessica J ^a,b  

^a Columbia University ^*  (United States)

^b KYOTO UNIVERSITY   (Japan)

Author keywords

Angiogenesis; Anti VEGF antibody; Rhabdoid tumor of the kidney; Vascular endothelial growth factor

Indexed keywords

VASCULOTROPIN;

ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; CANCER SURVIVAL; CONFERENCE PAPER; CONTROLLED STUDY; ENDOTHELIUM CELL; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; KIDNEY TUMOR; MOUSE; NICK END LABELING; NONHUMAN; PRIORITY JOURNAL; RHABDOID TUMOR; TUMOR GROWTH; TUMOR VASCULARIZATION; TUMOR XENOGRAFT; VASCULAR ENDOTHELIUM;

EID: 0036191641     PISSN: 00223468     EISSN: None     Source Type: Journal    
DOI: 10.1053/jpsu.2002.30859     Document Type: Conference Paper

References (11)

1. Renal tumors
2. Primary malignant rhabdoid tumor of the central nervous system
3. Successful treatment of a patient with stage IV malignant rhabdoid tumor of the kidney: Case report and review
4. Rhabdoid tumor of the kidney: A clinicopathologic study of 22 patients from the International Society of Paediatric Oncology (SIOP) nephroblastoma file
5. Anti-VEGF antibody suppresses primary tumor growth and metastasis in an experimental model of Wilms' tumor
6. Suppression of primary tumor growth in a mouse model of human neuroblastoma
7. Highly specific anti-angiogenic therapy is effective in suppressing growth of experimental Wilms tumor
8. Complete inhibition of rhabdomyosarcoma xenograft growth and neovascularization requires blockade of both tumor and host vascular endothelial growth factor
9. Selective ablation of immature blood vessels in established human tumors follows vascular endothelial growth factor withdrawal
10. Direct actions of angiopoietin-1 on human endothelium: Evidence for network stabilization, cell survival, and interaction with other angiogenic growth factors
11. The G401 cell line, utilized for studies of chromosomal changes in Wilms' tumor, is derived from a rhabdoid tumor of the kidney