Vascular KATP channel blockade by glibenclamide, but not by acarbose, in patients with Type II diabetes

Clinical Science

Volumn 102, Issue 3, 2002, Pages 307-314

  Abbink, E J ^a   Pickkers, P ^a   Van Rosendaal, A Jansen ^a   Lutterman, J A ^a   Tack, C J ^a   Russel, F G M ^a   Smits, P ^a  

^a RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Acarbose; Acetylcholine; Diazoxide; Dipyridamole; Glibenclamide; KATP channel; Reactive hyperaemia; Type II diabetes mellitus; Vascular

Indexed keywords

ACARBOSE; ACETYLCHOLINE; DIAZOXIDE; DIPYRIDAMOLE; GLIBENCLAMIDE; POTASSIUM CHANNEL BLOCKING AGENT;

ARTICLE; CHANNEL GATING; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; DOUBLE BLIND PROCEDURE; DRUG EFFECT; HUMAN; ISCHEMIA; LIMB BLOOD FLOW; NON INSULIN DEPENDENT DIABETES MELLITUS; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; VASODILATATION;

ACARBOSE; ACETYLCHOLINE; CROSS-OVER STUDIES; DIABETES MELLITUS, TYPE 2; DIAZOXIDE; DIPYRIDAMOLE; DOUBLE-BLIND METHOD; FEMALE; FOREARM; GLYBURIDE; HUMANS; HYPOGLYCEMIC AGENTS; ISCHEMIA; MALE; MIDDLE AGED; PLETHYSMOGRAPHY; POTASSIUM CHANNEL BLOCKERS; VASODILATOR AGENTS;

EID: 0036191487     PISSN: 01435221     EISSN: None     Source Type: Journal    
DOI: 10.1042/CS20010175     Document Type: Article

References (37)

1. Epidemiology of some peripheral arterial findings in diabetic men and women: Experiences from the Framingham study
2. Mortality from coronary heart disease and stroke in relation to degree of glycaemia: The Whitehall study
3. Diabetic retinopathy and cardiovascular disease in type II diabetics. The Framingham Heart Study and the Framingham Eye Study
4. Epidemiology and public health aspects of non-insulin-dependent diabetes mellitus
5. Sulfonylureas in NIDDM
6. Oral hypoglycemic agents
7. ATP-regulated K+ channels in cardiac muscle
8. Hyperpolarizing vasodilators activate ATP-sensitive K+ channels in arterial smooth muscle
9. Potassium channel openers and vascular smooth muscle relaxation
10. ATP-sensitive potassium channel modulation of the guinea pig ventricular action potential and contraction
11. Hyperpolarization and relaxation of resistance arteries in response to adenosine diphosphate. Distribution and mechanism of action
12. ATP-regulated K+ channels protect the myocardium against ischemia/reperfusion damage
13. Comparison of KRN2391 with nicorandil and nifedipine on canine coronary blood flow: Antagonism by glibenclamide
14. Blockade of the ATP-sensitive potassium channel modulates reactive hyperemia in the canine coronary circulation
15. Blockade of ATP-sensitive potassium channels prevents myocardial preconditioning in dogs
16. Interaction of sulphonylurea derivatives with vascular ATP-sensitive potassium channels in humans
17. Blockade of vascular ATP-sensitive potassium channels reduces the vasodilator response to ischaemia in humans
18. The measurement of volume changes in human limbs
19. Caffeine and theophylline attenuate adenosine-induced vasodilation in humans
20. Role of the wrist cuff in forearm plethysmography
21. Nitric oxide hyperpolarizes rabbit mesenteric arteries via ATP-sensitive potassium channels
22. Calcium channels, potassium channels, and voltage dependence of arterial smooth muscle tone
23. Coupling of ATP-sensitive K+ channels to A1 receptors by G proteins in rat ventricular myocytes
24. Maximal post-ischaemic forearm vasodilation in human hypertension: A re-assessment of the method
25. Reactions of the blood vessels of the human forearm to increases in transmural pressure
26. Measuring forearm blood flow and interpreting the responses to drugs and mediators
27. How reproducible is bilateral forearm: Plethysmography?
28. Acute effects of oral glibenclamide on blood pressure and forearm vascular resistance in diabetics
29. Comparative effects of glibenclamide and metformin on ambulatory blood pressure and cardiovascular reactivity in NIDDM
30. Metformin improves peripheral vascular flow in nonhyperlipidemic patients with arterial disease
31. Improved endothelial function with metformin in type 2 diabetes mellitus
32. In vivo endothelial dysfunction characterizes patients with impaired fasting glucose
33. Acute hyperglycemia attenuates endothelium-dependent vasodilation in humans in vivo
34. Effect of insulin on acetylcholine-induced vasodilation in normotensive subjects and patients with essential hypertension
35. Impaired vasodilation of forearm resistance vessels in hypercholesterolemic humans
36. Impaired endothelium-dependent vasodilation of forearm resistance vessels in hypercholesterolaemia