Lactoferrin: Influences on Langerhans cells, epidermal cytokines, and cutaneous inflammation

Biochemistry and Cell Biology

Volumn 80, Issue 1, 2002, Pages 103-107

  Kimber, I ^a   Cumberbatch, M ^a   Dearman, R J ^a   Headon, D R ^a   Bhushan, M ^a   Griffiths, C E M ^a  

^a JEALOTT S HILL INTERNATIONAL RESEARCH CENTRE   (United Kingdom)

Author keywords

Interleukin 1 ; Lactoferrin; Langerhans cells; Tumor necrosis factor

Indexed keywords

CELLS; PROTEINS; TUMORS;

EPIDERMAL CYTOKINES;

BIOCHEMISTRY;

ALLERGEN; CD1 ANTIGEN; CYTOKINE; DIPHENCYPRONE; HLA DR ANTIGEN; INTERLEUKIN 1BETA; LACTOFERRIN; TUMOR NECROSIS FACTOR ALPHA;

CONFERENCE PAPER; CYTOKINE PRODUCTION; EPIDERMIS; HUMAN; LANGERHANS CELL; PROTEIN EXPRESSION; PUNCH BIOPSY; REDUCTION; REGULATORY MECHANISM; SKIN INFLAMMATION; STEM CELL MOBILIZATION;

ADMINISTRATION, TOPICAL; CELL MOVEMENT; CYTOKINES; EPIDERMIS; HUMANS; INFLAMMATION; LACTOFERRIN; LANGERHANS CELLS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0036191474     PISSN: 08298211     EISSN: None     Source Type: Journal    
DOI: 10.1139/o01-227     Document Type: Conference Paper

References (32)

1. Functional caspase-1 is required for Langerhans cell migration and optimal contact sensitisation in mice
2. Identification of the bactericidal domain of lactoferrin
3. Lactoferrin: A multifunctional immunoregulatory protein
4. Role of iron in bacterial infection
5. Dermal tumour necrosis factor-α induces dendritic cell migration to draining lymph nodes, and possibly provides one stimulus for Langerhans cell migration
6. Tumour necrosis factor-α is required for accumulation of dendritic cells in draining lymph nodes and for optimal contact sensitization
7. Modulation of epidermal Langerhans cell frequency by tumour necrosis factor-α
8. Interleukin 1β and the stimulation of Langerhans cell migration: Comparisons with tumour necrosis factor α
9. Langerhans cells require signals from both tumour necrosis factor-α and interleukin-1β for migration
10. Langerhans cell migration in mice requires intact type 1 interleukin 1 receptor (IL-1RI) function
11. Inhibition by dexamethasone of Langerhans cell migration: Influence of epidermal cytokine signals
12. Tumour necrosis factor-α induces Langerhans cell migration in humans
13. Regulation of epidermal Langerhans cell migration by lactoferrin
14. Interleukin (IL)-18 induces Langerhans cell migration by a tumour necrosis factor-α- and IL-1β-dependent mechanism
15. Early molecular events in the induction phase of contact sensitivity
16. Exogenous topical lactoferrin inhibits allergen-induced Langerhans cell migration and cutaneous inflammation in humans
17. Dendritic cells and cutaneous immune responses to chemical allergens
18. Langerhans cells and cellular interactions
19. Regulation by lactoferrin of epidermal Langerhans cell migration
20. Cytokines and chemokines in the initiation and regulation of epidermal Langerhans cell migration
21. Lactoferrin and regulation of cutaneous immunity and inflammation
22. Lactoferrin: Molecular structure and biological function
23. Lactoferrin regulates the release of tumour necrosis factor alpha and interleukin 6 in vivo
24. Lactoferrin in milk from different species
25. An iron-binding protein common to many external secretions
26. Lactoferrin, an iron binding protein in neutrophilic leukocytes
27. Lactoferrin down-regulates the activity of granulocyte macrophage colony-stimulating factor promoter in interleukin-1 β-stimulated cells
28. Biological role of lactoferrin
29. Murine epidermal Langerhans cells mature into potent immunostimulatory den-dritic cells in vitro
30. In vitro evidence that Langerhans cells can adopt two functionally distinct forms capable of antigen presentation to T lymphocytes
31. Tumour necrosis factor receptor II (p75) signalling is required for the migration of Langerhans cells
32. A system for production of commercial qualtities of human lactoferrin: A broad spectrum natural antibiotic