Differences in reactivity of antibodies to active versus inactive PLTP significantly impacts PLTP measurement

Journal of Lipid Research

Volumn 43, Issue 2, 2002, Pages 281-289

  Murdoch, Susan J ^a   Wolfbauer, Gertrud ^a   Kennedy, Hal ^a   Marcovina, Santica M ^a   Carr, Molly C ^a   Albers, John J ^a,b  

^a UNIVERSITY OF WASHINGTON   (United States)

^b Northwest Research Laboratory   (United States)

Author keywords

Apolipoprotein A I; Apolipoprotein E; High density lipoprotein; Lipoprotein distribution; Phospholipid transfer protein

Indexed keywords

HIGH DENSITY LIPOPROTEIN; ISOPROTEIN; LOW DENSITY LIPOPROTEIN; MONOCLONAL ANTIBODY; PHOSPHOLIPID TRANSFER PROTEIN; PHOSPHOLIPID TRANSFER PROTEIN ANTIBODY; POLYCLONAL ANTIBODY; PROTEIN ANTIBODY; UNCLASSIFIED DRUG;

ANTIBODY SPECIFICITY; ANTIGEN BINDING; ARTICLE; CONTROLLED STUDY; CORRESPONDENCE ANALYSIS; DOT HYBRIDIZATION; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME BLOOD LEVEL; FAST PROTEIN LIQUID CHROMATOGRAPHY; FEMALE; GEL ELECTROPHORESIS; HUMAN; IMMUNOREACTIVITY; MALE; MOLECULAR WEIGHT; NORMAL HUMAN; PARTICLE SIZE; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; QUANTITATIVE ASSAY; WESTERN BLOTTING;

ADULT; ANTIBODIES, MONOCLONAL; ANTIBODY SPECIFICITY; ANTIGEN-ANTIBODY REACTIONS; CARRIER PROTEINS; CHOLESTEROL, HDL; CHOLESTEROL, LDL; ENZYME ACTIVATION; FEMALE; HUMANS; IMMUNOBLOTTING; MALE; MEMBRANE PROTEINS; PHOSPHOLIPID TRANSFER PROTEINS;

EID: 0036186710     PISSN: 00222275     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (21)

1. Mass concentration of plasma phospholipid transfer protein in normolipidemic, type IIa hyperlipidemic, type IIb hyperlipidemic, and non-insulin-dependent diabetic subjects as measured by a specific ELISA
2. Quantification of human plasma phospholipid transfer protein (PLTP): Relationship between PLTP mass and phospholipid transfer activity
3. Measurement of human plasma phospholipid transfer protein by sandwich ELISA
4. Distribution of phospholipid transfer protein in human plasma: Presence of two forms of phospholipid transfer protein, one catalytically active and the other inactive
5. Plasma phospholipid transfer protein enhances transfer and exchange of phospholipids between very low density lipoproteins and high density lipoproteins during lipolysis
6. Phospholipid transfer protein mediates transfer of not only phosphatidylcholine but also cholesterol from phosphatidylcholine-cholesterol vesicles to high density lipoproteins
7. Effect of lipid transfer proteins on lipoprotein lipase induced transformation of VLDL and HDL
8. Phospholipid transfer protein gene knock-out mice have low high density lipoprotein levels, due to hypercatabolism, and accumulate apoA-IV-rich lamellar lipoproteins
9. High density lipoprotein conversion mediated by human plasma phospholipid transfer protein
10. Human plasma phospholipid transfer protein causes high density lipoprotein conversion
11. Phospholipid transfer protein enhances removal of cellular cholesterol and phospholipids by high-density lipoprotein apolipoproteins
12. PLTP activity in premenopausal women. Relationship with lipoprotein lipase, HDL, LDL, body fat, and insulin resistance
13. Altered particle size distribution of apolipoprotein A-I-containing lipoproteins in subjects with coronary artery disease
14. Effect of adiposity on plasma lipid transfer protein activities: A possible link between insulin resistance and high density lipoprotein
15. Plasma phospholipid transfer protein activity is related to insulin resistance: Impaired acute lowering by insulin in obese Type II diabetic patients
16. Enzymatic methods for quantification of lipoprotein lipids
17. Plasma phospholipid mass transfer rate: Relationship to plasma phospholipid and cholesteryl ester transfer activities and lipid parameters
18. Functional expression of human and mouse plasma phospholipid transfer protein: Effect of recombinant and plasma PLTP on HDL subspecies
19. A simple, nonchromatographic procedure to purify immunoglobulins from serum and ascites fluid
20. Immunochemical characterization of six monoclonal antibodies to human apolipoprotein A-I: Epitope mapping and expression
21. Lipid transfer inhibitor protein defines the participation of lipoproteins in lipid transfer reactions: CETP has no preference for cholesteryl esters in HDL versus LDL