Involvement of mechanical stretch in the gelatinolytic activity of the fibrous sclera of chicks, in vitro

Japanese Journal of Ophthalmology

Volumn 46, Issue 1, 2002, Pages 24-30

  Fujikura, Hajime ^a   Seko, Yuko ^a   Tokoro, Takashi ^a   Mochizuki, Manabu ^a   Shimokawa, Hitoyata ^a  

^a TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

Author keywords

Extracellular matrix; Matrix metalloproteinase 2; Mechanical stretch; Myopia; Sclera

Indexed keywords

4 AMINOPHENYLMERCURIC ACETATE; GELATIN; GELATINASE A; MESSENGER RNA; RNA; TISSUE INHIBITOR OF METALLOPROTEINASE 2;

ALKYLATION; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CHICK EMBRYO; CONTROLLED STUDY; CULTURE MEDIUM; CYTOPLASM; EMBRYO; ENZYME REGULATION; EXTRACELLULAR MATRIX; FIBROBLAST; IN VITRO STUDY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; REDUCTION; RNA EXTRACTION; SCLERA; STRETCHING; ZYMOGRAPHY;

ANIMALS; BLOTTING, NORTHERN; CELLS, CULTURED; CHICK EMBRYO; DNA PRIMERS; EXTRACELLULAR MATRIX; FIBROBLASTS; GELATIN; MATRIX METALLOPROTEINASE 2; RNA, MESSENGER; SCLERA; STRESS, MECHANICAL; TISSUE INHIBITOR OF METALLOPROTEINASE-2;

EID: 0036184119     PISSN: 00215155     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0021-5155(01)00451-8     Document Type: Article

References (32)

1. Extreme myopia produced by modest changes in early visual experience
2. Scleral changes in chicks with form-deprivation myopia
3. Scleral change in experimentally myopic monkeys
4. Growth of two layers of the chick sclera is modulated reciprocally by visual conditions
5. Increased latent gelatinase activity in the sclera of visually deprived chicks
6. Simulated glomerular pressure modulates mesangial cell 72 kDa metalloproteinase activity
7. Regulation of extracellular matrix by mechanical stress in rat glomerular mesangial cells
8. Stretch-induced membrane type matrix metalloproteinase and tissue plasminogen activator in cardiac fibroblast cells
9. The relationship of choroidal blood-flow and accommodation to the control of ocular growth
10. A longitudinal investigation of adult-onset and adult-progression of myopia in an occupational group
11. Choroidal stress and emmetropization
12. Scleral growth is influenced by retinal pigment epithelium in vitro
13. Scleral fibroblasts of chick embryo proliferate by an autocrine mechanism in protein-free primary cultures: Depending on the growth state
14. A new vacuum-operated stress-providing instrument that applies static or variable duration cycle tension or compression to cells in vitro
15. Mechanical load induces sarcoplasmic wounding and FGF release in differentiated human skeletal muscle cultures
16. Matrix metalloproteinases and their inhibitors in connective tissue remodeling
17. Matrix metalloproteinase
18. H-ras oncogene-transformed human bronchial epithelial cells (TBE-1) secrete a single metalloproteinase capable of degrading basement membrane collagen
19. The activation of human type IV collagenase proenzyme
20. The cystein switch: A principle of regulation of metalloproteinase activity with potential applicability to the entire matrix metalloproteinase gene family
21. Multiple modes of activation of latent human fibroblast collagenase; evidence for the role of a cys-73 active-site zinc complex in latency and a cystein switch mechanism for activation
22. Expression of metalloproteinases and tissue inhibitors of metalloproteinases in human osteoblast-like cells; differentiation is associated with repression of metalloproteinase biosynthesis
23. A metalloproteinase from human rheumatoid synovial fibroblasts that digests connective tissue matrix components
24. Inhibition of autoproteolytic activation of interstitial procollagenase by recombinant metalloproteinase inhibitor MI/TIMP-2
25. Regulation of the autoactivation of human 72-kDa progelatinase by tissue inhibitor of metalloproteinases-2
26. Matrix metalloproteinase 9 (92 kDa gelatinase/type IV collagenase) from HT 1080 human fibrosarcoma cells. Purification and activation of the precursor and enzymatic properties
27. Hybridization of denatured RNA and small DNA fragments transferred to nitrocellulose
28. Activation of progelatinase (MMP9) by gelatinase A (MMP2)
29. Matrix metalloproteinase-2 is an interstitia1 collagenase. Inhibitor-free enzyme catalyzes the cleavage of co1lagen fibrils and soluble native type I collagen generating the specific 3/4 and 1/4 1ength fragments
30. Regional proteoglycan synthesis in the sclera of experimentally myopic chicks
31. Gelatinase A and TIMP-2 expression in the fibrous sclera of myopic and recovering chick eyes