The pharmacokinetics and cardiovascular effects of a single intravenous dose of protamine in normal volunteers

Anesthesia and Analgesia

Volumn 94, Issue 3, 2002, Pages 514-522

  Butterworth, John ^a   Lin, Yonggu A ^a   Prielipp, Richard ^a   Bennett, Judy ^a   James, Robert ^a  

^a WAKE FOREST SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PROTAMINE;

ADULT; ARTICLE; DOSE RESPONSE; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG EFFECT; DRUG ELIMINATION; HUMAN; HUMAN EXPERIMENT; MICHAELIS CONSTANT; NORMAL HUMAN; PRIORITY JOURNAL; SEX DIFFERENCE;

EID: 0036180570     PISSN: 00032999     EISSN: None     Source Type: Journal    
DOI: 10.1097/00000539-200203000-00008     Document Type: Article

References (13)

1. Insulin, oral hypoglycemic agents, and the pharmacology of the endocrine pancreas
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3. Adverse events after protamine administration in patients undergoing cardiopulmonary bypass: Risks and predictors of under-reporting
4. Heparin neutralization
5. Protamine sulphate inhibits platelet membrane glycoprotein IB-von Willebrand factor activity
6. The effects of heparin, protamine, and heparinase 1 on platelets in vitro using whole blood flow cytometry
7. Reversible block of the calcium release channel/ryanodine receptor by protamine, a heparin antidote
8. Determination of protamine sulphate in drug formulations using high performance liquid chromatography
9. Schwartz criterion
10. Anticoagulation monitoring during cardiac surgery: A review of current and emerging technologies
11. The heparin-protamine interaction: A review
12. Hemostatic effects of low-dose protamine following cardiopulmonary bypass