Cytochrome P450 2C19 gene polymorphism in four Chinese nationality populations

Chinese Journal of Medical Genetics

Volumn 19, Issue 1, 2002, Pages 52-54

  Zhang, Song ^a   Dong, Zhaowen ^a   Tang, Li ^a   Zhou, Qiang ^a   Wu, Zhanpeng ^a  

^a NATIONAL RESEARCH INSTITUTE FOR FAMILY PLANNING   (China)

Author keywords

Cytochrome P450 2C19; Genotype; Polymerase chain reaction; Restriction fragment length polymorphism

Indexed keywords

GENES; POPULATION STATISTICS;

CYTOCHROME;

GENETIC ENGINEERING;

CYTOCHROME P450 2C19;

ARTICLE; CHINESE; GENE FREQUENCY; GENETIC POLYMORPHISM; GENOTYPE; HUMAN; POLYMERASE CHAIN REACTION; RESTRICTION FRAGMENT LENGTH POLYMORPHISM;

AFRICAN CONTINENTAL ANCESTRY GROUP; ARYL HYDROCARBON HYDROXYLASES; ASIAN CONTINENTAL ANCESTRY GROUP; CHINA; CYTOCHROME P-450 ENZYME SYSTEM; EUROPEAN CONTINENTAL ANCESTRY GROUP; GENE FREQUENCY; GENETICS, POPULATION; HUMANS; MIXED FUNCTION OXYGENASES; POLYMERASE CHAIN REACTION; POLYMORPHISM, GENETIC; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH;

EID: 0036179091     PISSN: 10039406     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (7)

1. Pronounced differences between native Chinese and Swedish populations in the polymorphic hydroxylation of debrisoquin and S-mephenytoin
2. Geographical/interracial differences in polymorphic drug oxidation
3. High and variable frequencies of CYP2C19 mutations: Medical consequences of poor drug metabolism in Vanuatu and other Pacific islands
4. Individual and ethnic differences in CYP2C19 activity in Chinese populations
5. The major genetic defect responsible for the polymorphism of S-mephenytoin metabolism in humans
6. Genotyping of S-mephenytoin hydroxylase in a Chinese population
7. Allele, genotypic and phenotypic distributions of S-mephenytoin 4′-hydroxylase (CYP2C19) in healthy Caucasia populations of European descent throughout the world