Radioprotection of lung and esophagus by overexpression of the human manganese superoxide dismutase transgene

Military Medicine

Volumn 167, Issue 2 SUPPL., 2002, Pages 71-73

  Epperly, Michael W ^a   Defilippi, Stacy ^a   Sikora, Chrisitine ^a   Gretton, Joan ^a   Greenberger, Joel S ^a  

^a UNIVERSITY OF PITTSBURGH CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

LIPOSOME; MANGANESE SUPEROXIDE DISMUTASE; METALLOTHIONEIN;

ANIMAL EXPERIMENT; CELL SURVIVAL; CONFERENCE PAPER; CONTROLLED STUDY; ESOPHAGITIS; ESOPHAGUS; GENE OVEREXPRESSION; LUNG; LUNG TUMOR; MOUSE; NONHUMAN; PLASMID; RADIATION INJURY; RADIATION PROTECTION; TRANSGENE;

EID: 0036177254     PISSN: 00264075     EISSN: None     Source Type: Journal    
DOI: 10.1093/milmed/167.suppl_1.71     Document Type: Conference Paper

References (5)

1. Prevention of late effects of irradiation lung damage by MnSOD gene therapy
2. Prevention of irradiation-induced esophagitis by plasmid/liposome delivery of the human manganese superoxide dismutase transgene
3. 1/S phase cell cycle arrest
4. Intratracheal injection of adenovirus containing the human MnSOD transgene protects athymic nude mice from irradiation-induced organizing alveolitis
5. Human MnSOD transgene expression inhibits apoptosis induced by IL-3 withdrawal or TNF-α exposure as well as ionizing irradiation in 32D cl 3 murine hematopoietic progenitor cells