Age-associated decrease in 8-hydroxy-2′-deoxyguanosine (8-OHdG) immunoreactivity in the autopsied brain

Legal Medicine

Volumn 4, Issue 1, 2002, Pages 29-33

  Nogami, Makoto ^a   Shiga, Junji ^a   Inuzuka, Noriko ^a   Takatsu, Akihiro ^b  

^a TEIKYO UNIVERSITY   (Japan)

^b JIKEI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Autopsy; Brain infarction; Hydroxydeoxyguanosine; Immunohistochemistry

Indexed keywords

8 HYDROXYDEOXYGUANOSINE; DNA BASE; REACTIVE OXYGEN METABOLITE;

ADULT; AGE; AGED; ARTICLE; AUTOPSY; BRAIN INFARCTION; COMPARATIVE STUDY; CONTROLLED STUDY; CORRELATION FUNCTION; FEMALE; FORENSIC PATHOLOGY; GLIA CELL; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; MALE; PRESCHOOL CHILD; REPERFUSION; SENSITIVITY AND SPECIFICITY; STATISTICAL ANALYSIS;

EID: 0036176215     PISSN: 13446223     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1344-6223(01)00059-1     Document Type: Article

References (4)

1. Immunohistochemical detection of oxidative DNA damage induced by ischemia-reperfusion insults in gerbil hippocampus in vivo
2. Age-associated accumulation of 8-hydroxydeoxyguanosine in mitochondrial DNA of human diaphragm
3. High levels of 8-hydroxy-2′-deoxyguanosine appear in normal human epidermis after a single dose of ultraviolet radiation
4. RNA oxidation is a prominent feature of vulnerable neurons in Alzheimer's disease