Perspectives fulfilled: The work and thought of J. V. Neel (1915-2000)

Perspectives in Biology and Medicine

Volumn 45, Issue 1, 2002, Pages 46-64

  Weiss, Kenneth M ^a   Schull, William J ^a  

^a PENNSYLVANIA STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTHROPOLOGY; ATOMIC BOMB; BIOLOGY; DNA SEQUENCE; EVOLUTION; GENE MUTATION; GENETIC VARIABILITY; HUMAN; HUMAN GENETICS; HUMAN GENOME; LONGEVITY; NUCLEAR ACCIDENT; POPULATION RESEARCH; PRIORITY JOURNAL; PUBLIC HEALTH; REVIEW; VACCINATION;

EID: 0036175437     PISSN: 00315982     EISSN: None     Source Type: Journal    
DOI: 10.1353/pbm.2002.0020     Document Type: Review

References (68)

1. The distribution of the sickle-cell trait in East Africa and elsewhere and its apparent relationship to the incidence of subtertian malaria
2. Protection afforded by sickle-cell trait against subtertian malarial infection
3. Sickle cell disease in the Balovale District of Northern Rhodesia
4. Long DOP-PCR of rare archival anthropological samples
5. Some possibilities for measuring selection intensities in man
6. Genetics of retinoblastoma
7. The Croonian lectures on inborn errors of metabolism
8. Genetic effects of the atomic bombs in Hiroshima and Nagasaki
9. The effect of variation on fitness
10. Disease and Evolution
11. A molecular approach to the study of genic heterozygosity in natural populations. I. The number of alleles at different loci in Drosophila pseudoobscura
12. The average number of generations until extinction of an individual mutant gene in a finite population
13. A molecular approach to the study of genic heterozygosity in natural populations. II. Amount of variation and degree of heterozygosity in natural populations of Drosophila pseudoobscura
14. A simulation of the fate of a mutant gene of neutral selective value in a primitive population
15. Genetic epidemiology
16. An estimate of the mutational damage in man from data on consanguineous marriages
17. Artificial transmutation of the gene
18. The production of mutations
19. Our load of mutations
20. The detection of the genetic carriers of hereditary disease
21. The inheritance of sickle cell anemia
22. The population genetics of two inherited blood dyscrasias in man
23. Editorial. Medicine's genetic horizon
24. The study of natural selection in primitive and civilized populations
25. Diabetes mellitus: A "thrifty" genotype rendered detrimental by "progress"?
26. Between two worlds. The William Allan Award Lecture for 1965
27. Lessons from a "primitive" people
28. The thrifty genotype revisited
29. Problem of "false positive" conclusions in genetic epidemiology: Lessons from the leukemia cluster near the Sellafield nuclear installation
30. Coming events casting shadows ahead
31. Looking ahead: Some genetic issues of the future
32. Changing perspectives on the genetic doubling dose of ionizing radiation for humans, mice, and Drosophila
33. Two recent radiation-related genetic false alarms: Leukemia in West Cumbria, England, and minisatellite mutations in Belarus
34. In the beginning...
35. Some ethical issues at the population level raised by "soft" eugenics, euphenics, and isogenics
36. The rate of mutation of the gene responsible for retinoblastoma in man
37. The comparative radiation genetics of humans and mice
38. On some trends in understanding the genetics of man
39. Hematologic and genetic study of the transmission of thalassemia (Cooley's anemia, Mediterranean anemia)
40. Type II diabetes, essential hypertension, and obesity as "syndromes of impaired genetic homeostasis": The "thrifty genotype" hypothesis enters the 21st century
41. Notes on the effect of measles and measles vaccine in a virgin-soil population of South American Indians
42. Adapting two-dimensional gel electrophoresis to the study of human germ-line mutation rates
43. Implications of the Hiroshima-Nagasaki genetic studies for the estimation of the human "doubling dose" of radiation
44. Estimation of mutation rate from rare protein variants
45. Sickle cell anemia: A molecular disease
46. A genetic study of multiple polyposis of the colon (with an appendix deriving a method of estimating relative fitness)
47. Huntington's chorea in Michigan. II. Selection and mutation
48. Identification of genetic variants in erythrocyte lysate by two-dimensional gel electrophoresis
49. Estimation of expected number of rare alleles of a locus and calculation of mutant rate
50. James Van Gundia Neel
51. The effects of parental consanguinity and inbreeding in Hirdao, Japan. V. Summary and interpretation
52. Genetic effects of the atomic bombs: A reappraisal
53. Congenital aniridia
54. Cancer risk among atomic bomb survivors: The RERF Life Span Study
55. Studies of the mortality of atomic bomb survivors. Report 12, Part II. Noncancer mortality: 1950-1990
56. An algorithm for comparing two-dimensional electrophoretic gels, with particular reference to the study of mutation
57. James V. Neel, M.D., Ph.D. (March 22, 1915-January 31, 2000): Founder effect