In utero exposure to immunosuppressive drugs

Biology of the Neonate

Volumn 81, Issue 2, 2002, Pages 73-81

  Prévot, Anne ^a   Martini, Stephan ^a   Guignard, Jean Pierre ^a  

^a LAUSANNE UNIVERSITY HOSPITAL   (Switzerland)

Author keywords

Autoimmune diseases; Cyclosporine; Immunosuppressive drugs; Infant, newborn; Intrauterine growth retardation; Nephrogenesis; Pregnancy; Prematurity; Prenatal exposure, delayed effects; Transplantation

Indexed keywords

AZATHIOPRINE; BETAMETHASONE; CALCINEURIN; CALCINEURIN INHIBITOR; CHLORAMBUCIL; CORTICOSTEROID; CYCLOPHOSPHAMIDE; CYCLOSPORIN A; DEXAMETHASONE; IMMUNOSUPPRESSIVE AGENT; INTERLEUKIN 2; INTERLEUKIN 2 RECEPTOR ANTIBODY; MERCAPTOPURINE; METHOTREXATE; MYCOPHENOLIC ACID; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; OKT 3; PREDNISOLONE; PREDNISONE; TACROLIMUS;

ADRENAL INSUFFICIENCY; BONE MARROW SUPPRESSION; BREAST FEEDING; CHROMOSOME ABERRATION; DIABETES MELLITUS; FATHER; FERTILITY; FOLLOW UP; GRAFT REJECTION; HUMAN; HYPERKALEMIA; IMMUNOPATHOLOGY; IMMUNOSUPPRESSIVE TREATMENT; INCIDENCE; INFLAMMATORY DISEASE; INTRAUTERINE GROWTH RETARDATION; KIDNEY FAILURE; LOW BIRTH WEIGHT; MATERNAL HYPERTENSION; NEPHRON; NEPHROTOXICITY; NONHUMAN; PERINATAL MORTALITY; PREECLAMPSIA; PREGNANCY; PREMATURITY; PRENATAL DRUG EXPOSURE; PRIORITY JOURNAL; REVIEW; TRANSPLANTATION;

FEMALE; FETAL GROWTH RETARDATION; HUMANS; IMMUNOSUPPRESSIVE AGENTS; INFANT, LOW BIRTH WEIGHT; INFANT, NEWBORN; INFANT, PREMATURE; MALE; MATERNAL-FETAL EXCHANGE; PREGNANCY;

EID: 0036174420     PISSN: 00063126     EISSN: None     Source Type: Journal    
DOI: 10.1159/000047187     Document Type: Review

References (58)

1. Report from the National Transplantation Pregnancy Registry (NTPR): Outcomes of pregnancy after transplantation
2. Immunosuppressive drug use during pregnancy
3. Effects of immunosuppressive drugs during pregnancy
4. Drug safety issues in pregnancy following transplantation and immunosuppression. Effects and outcomes
5. Pregnancy in chronic renal insufficiency and end-stage renal disease
6. Planned pregnancy in a renal transplant recipient
7. Pregnancy in women with renal allografts
8. Dialysis, transplantation, and pregnancy
9. The effect of pregnancy on kidney function in renal allograft recipients
10. Grossesse aprés greffes d'organe
11. Outcomes of 500 pregnancies in 335 female kidney, liver, and heart transplant recipients
12. Systemic lupus erythematosus
13. Prednisone dosage and pregnancy outcome in renal allograft recipients
14. The relative contribution of prematurity and fetal growth retardation to low birth-weight in developing and developed societies
15. Intrauterine growth retardation-perinatal mortality and postnatal morbidity in a perinatal center
16. Befunde bei Neugeborenen nierentransplantierter Mütter
17. Analysis of 629 pregnancy outcomes in transplant recipients treated with Sandimmun
18. Renal function of children exposed to cyclosporin in utero
19. Pregnancy after liver transplantation under tacrolimus
20. Pregnancy outcome in renal allograft recipients in Norway. The importance of im-munosuppressive drug regimen and health status before pregnancy
21. National transplantation pregnancy registry: Report on outcomes in cy-closporine-treated female kidney transplant recipients with an interval from transplant to pregnancy of greater than five years
22. Pregnancy in renal transplant patients: 45 case reports
23. Nouveau-nés de mères transplant́es rénales
24. Thirty-three pregnancies in a population of 1,725 renal transplant patients
25. Variables affecting birthweight and graft survival in 197 pregnancies in cyclosporine-treated female kidney transplant recipients
26. Review of the course and outcome of 100 pregnancies in 84 women treated with tacrolimus
27. Le Prématuré;
28. Retard de croissance intra-utérin;
29. Low birth weights contribute to the high rates of early-onset chronic renal failure in the Southern United States
30. Relationship between weight at birth and the number and size of renal glomeruli in humans: A histomorphometric study
31. Pregnancy and transplantation
32. The transplacental passage of prednisone and prednisolone in pregnancy near term
33. Nephron number: Variability is the rule. Causes and consequences
34. The effects of immunosuppressive and anti-inflammatory medications on fertility, pregnancy, and lactation
35. Outcomes of pregnancy and the management of immunosuppressive agents to minimize fetal risks in organ transplant patients
36. Maternal azathioprine therapy and depressed haemopoiesis in the babies of renal allograft patients
37. Pregnancy following kidney transplantation: Risk for offsprings
38. Immunological responses in an infant after cyclosporine A exposure during pregnancy
39. Immunological evaluation during the first year of life of infants born to cyclosporine-treated female kidney recipients
40. Analysis of peripheral blood lymphocyte populations and immune function from children exposed to cyclosporine or to azathioprine in utero
41. Long-term nephrotoxicity after exposure to cyclosporine in utero
42. Renal function of children born to transplanted women under cyclosporine A
43. In utero cyclosporine A (CsA) exposure and renal organogenesis in the rabbit
44. Dietary protein intake and the progressive nature of kidney disease: The role of hemodynamically mediated glomerular injury in the pathogenesis of progressive glomerular sclerosis in aging, renal ablation and intrinsic renal disease
45. Unilateral ureteral obstruction in neonatal rats leads to renal insufficiency in adulthood
46. Intrauterine food restriction as a determinant of offspring nephrosclerosis
47. Oligomeganephronic renal hypoplasia
48. Glomeruli and blood pressure. Less of one, more of the other?
49. Congenital oligonephropathy: The fetal flaw in essential hypertension?
50. Outcome of twin pregnancy in a renal transplant recipient treated with tacrolimus
51. Successful pregnancies in a combined pancreas and renal allograft recipient and in a renal graft recipient on tacrolimus treatment
52. Breast-feeding during treatment with cyclosporine
53. Successful breast feeding while mother was taking cyclosporin
54. Cyclosporine and pregnancy in the rat
55. Breast milk feeding and cognitive ability at 7-8 years
56. Paternity by cardiac transplant recipients
57. Effect of cyclosporine on fertility in male rats
58. Effect of Prograf (FK506) on spermatogenesis in rats