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Volumn 57, Issue 1, 2002, Pages 27-32

Synthesis and biological activity of some 4-substituted 1-[1-(2,3-dihydroxy-1-propoxy)methyl-1,2,3-triazol-(4 & 5)-ylmethyl]-1H-pyrazolo[3,4-d]pyrimidines

(7) Moukha chafiq, Omar a Taha, Mohamed Labd a Lazrek, Hassan Bihi b Vasseur, Jean Jacques c Pannecouque, Christophe d Witvrouw, Myriam d De Clercq, Erik d

a FACULTÉ DES SCIENCES (Morocco)

b FACULTÉ DES SCIENCES SEMLALIA (Morocco)

c UNIV MONTPELLIER (France)

d REGA INSTITUTE FOR MEDICAL RESEARCH (Belgium)

Author keywords

1,2,3 Triazole; Acyclic nucleosides; Biological evaluation; Pyrazolo 3,4 d pyrimidine

Indexed keywords

(3 ACETOXY 2 O BENZOYL 1 PROPOXY)METHYLAZIDE; (3 ACETOXY 2 O BENZOYL 1 PROPOXY)METHYLBROMIDE; 1 [1 (2,3 DIHYDROXY 1 PROPOXY)METHYL 1,2,3 TRIAZOL 4 YLMETHYL] 4 HYDROXY 1H PYRAZOLO[3,4 D]PYRIMIDINE; 1 [1 (2,3 DIHYDROXY 1 PROPOXY)METHYL 1,2,3 TRIAZOL 4 YLMETHYL] 4 METHOXY 1H PYRAZOLO[3,4 D]PYRIMIDINE; 1 [1 (2,3 DIHYDROXY 1 PROPOXY)METHYL 1,2,3 TRIAZOL 4 YLMETHYL] 4 METHYLAMINO 1H PYRAZOLO[3,4 D]PYRIMIDINE; 1 [1 (2,3 DIHYDROXY 1 PROPOXY)METHYL 1,2,3 TRIAZOL 4 YLMETHYL] 4 METHYLTHIO 1H PYRAZOLO[3,4 D]PYRIMIDINE; 1 [1 (2,3 DIHYDROXY 1 PROPOXY)METHYL 1,2,3 TRIAZOL 5 YLMETHYL] 4 METHYLTHIO 1H PYRAZOLO[3,4 D]PYRIMIDINE; 1 [1 (3 ACETOXY 2 O BENZOYL 1 PROPOXY)METHYL 1,2,3 TRIAZOL 4 YLMETHTL] 4 BENZYLTHIO 1H PYRAZOLO[3,4 D]PYRIMIDINE; 1 [1 (3 ACETOXY 2 O BENZOYL 1 PROPOXY)METHYL 1,2,3 TRIAZOL 4 YLMETHYL] 4 METHYLTHIO 1H PYRAZOLO[3,4 D]PYRIMIDINE; 1 [1 (3 ACETOXY 2 O BENZOYL 1 PROPOXY)METHYL 1,2,3 TRIAZOL 5 YLMETHYL] 4 BENZYLTHIO 1H PYRAZOLO[3,4 D]PYRIMIDINE; 1 [1 (3 ACETOXY 2 O BENZOYL 1 PROPOXY)METHYL 1,2,3 TRIAZOL 5 YLMETHYL] 4 METHYLTHIO 1H PYRAZOLO[3,4 D]PYRIMIDINE; 4 AMINO 1 [1 (2,3 DIHYDROXY 1 PROPOXY)METHYL 1,2,3 TRIAZOL 4 YLMETHYL] 1H PYRAZOLO[3,4 D]PYRIMIDINE; 4 BENZYLAMINO 1 [1 (2,3 DIHYDROXY 1 PROPOXY)METHYL 1,2,3 TRIAZOL 4 YLMETHYL] 1H PYRAZOLO[3,4 D]PYRIMIDINE; 4 BENZYLTHIO 1 [1 (2,3 DIHYDROXY 1 PROPOXY)METHYL 1,2,3 TRIAZOL 4 YLMETHYL] 1H PYRAZOLO[3,4 D]PYRIMIDINE; 4 BENZYLTHIO 1 [1 (2,3 DIHYDROXY 1 PROPOXY)METHYL 1,2,3 TRIAZOL 5 YLMETHYL] 1H PYRAZOLO[3,4 D]PYRIMIDINE; ACYCLIC NUCLEOSIDE; PYRIMIDINE DERIVATIVE; UNCLASSIFIED DRUG;

ANTIBACTERIAL ACTIVITY; ANTINEOPLASTIC ACTIVITY; ANTIVIRAL ACTIVITY; ARTICLE; CONTROLLED STUDY; CYCLOADDITION; DRUG SCREENING; DRUG SYNTHESIS; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS 2; ISOMER; MYCOBACTERIUM TUBERCULOSIS;

ANTIVIRAL AGENTS; CELLS, CULTURED; HIV-1; HIV-2; NUCLEOSIDES; PYRIMIDINES; STRUCTURE-ACTIVITY RELATIONSHIP; TRIAZOLES;

EID: 0036171878 PISSN: 0014827X EISSN: None Source Type: Journal
DOI: 10.1016/S0014-827X(01)01152-1 Document Type: Article

Times cited : (41)

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