Detection of DNA damage in mouse peripheral blood leukocytes by the comet assay after oral administration of monocrotophos

Drug and Chemical Toxicology

Volumn 25, Issue 1, 2002, Pages 65-74

  Mahboob, M ^a   Rahman, M F ^a   Danadevi, K ^a   Saleha Banu, B ^a   Grover, Paramjit ^a  

^a INDIAN INSTITUTE OF CHEMICAL TECHNOLOGY   (India)

Author keywords

[No Author keywords available]

Indexed keywords

MONOCROTOPHOS;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL VIABILITY; COMET ASSAY; CONTROLLED STUDY; CORRELATION COEFFICIENT; DIAGNOSTIC ACCURACY; DNA DAMAGE; DNA REPAIR; DNA STRAND BREAKAGE; DOSE TIME EFFECT RELATION; GENOTOXICITY; MALE; MOUSE; NONHUMAN; SENSITIVITY AND SPECIFICITY;

ADMINISTRATION, ORAL; ANIMALS; COMET ASSAY; DNA; DNA DAMAGE; LEUKOCYTES; MALE; MICE; MONOCROTOPHOS; MUTAGENS; PESTICIDES;

ANIMALIA;

EID: 0036171866     PISSN: 01480545     EISSN: None     Source Type: Journal    
DOI: 10.1081/DCT-100108472     Document Type: Article

References (34)

1. Effects of a new phosphorothionate (RPR-V) on ATPases and acetylcholinesterase in rat brain by subchronic dosing
2. Future of Indian pesticides industry in next millennium
3. Laboratory and field evaluation of SD 9129 as an insecticide
4. Formulation of monocrotophos
5. A survey of EPA/OPP and open literature data on selected pesticide chemicals tested for mutagenicity: I. Introduction and first ten chemicals
6. Pesticides and cancer
7. Study of pesticide genotoxicity
8. Further mutagenicity studies on pesticides in bacterial reversion assay systems
9. Structure-genotoxic activity relationships: Comparison of the results from several short term assays
10. Evaluation of the genetic activity profiles of 65 pesticides
11. An overview of short-term tests for the mutagenic and carcinogenic potential of pesticides
12. Mutagenicity of organophosphorous compounds in bacteria and Drosophila
13. Cytokinetic and cytogenetic effects of some agricultural chemicals on human lymphoid cell in vitro: Organophosphates
14. A simple technique for quantitation of low levels of DNA damage in individual cells
15. Assessment of genotoxic effects of Lindane
16. Mutagenicity of monocrotophos using micronucleus test in mice
17. Mutagenicity of monocrotophos in mice
18. Toxicology of monocrotophos
19. In vitro genotoxic effects of the insecticide deltamethrin in human peripheral blood leukocytes: DNA damage ('comet' assay) in relation to the induction of sister chromatid exchanges and micronuclei
20. DNA damaging effects of pesticides measured by the single cell gel electrophoresis assay (comet assay) and the chromosomal aberration test, in CHOK1 cells
21. Analysis of micronuclei and DNA single strand breaks in mouse splenocytes and peripheral lymphocytes after oral administration of tetramethylthiuram disulfide (Thiram)
22. Evaluation of genotoxic and cytotoxic properties of pesticides employed in Italian agricultural practices
23. Alkylation reaction of organophosphorous pesticides. Its chemical and biological significance
24. Mutagenicity studies on organophosphorus insecticides
25. Comparison of the mutagenic activity of eight organophosphorous insecticides in E. Coli
26. DNA strand breakage caused by dichlorovos methyl methanesulphonate and iodocetamide in Escherichia Coli and cultured Chinese hamster cells
27. Glutathione
28. Metabolism of monocrotophos in animals
29. Characterization of human microsomal Cyt.P-450 enzymes
30. Cytochrome P-450 IIBI, dealkylates nitrosamine induced adducts
31. Interaction of monocrotophos and its novel thiol analogues with microsomal cytochrome P-450: In vivo and in vitro studies in rat
32. Hepatic and extra hepatic glutathione depletion and glutathione-S-transferees inhibition by monocrotophos and its two thiol analogues