Neutrophil dysfunction in a case of glucose-6-phosphate dehydrogenase deficiency

American Journal of Pediatric Hematology/Oncology

Volumn 24, Issue 2, 2002, Pages 164-165

  Costa, Elísio ^a   Vasconcelos, Júlia ^a   Santos, Eugénia ^a   Laranjeira, Armando ^a   Melo, João Castroe ^a   Barbot, José ^a  

^a Serviço de Pediatria do Hospital de Santa Luzia de Viana do Castelo A L   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE 6 PHOSPHATE DEHYDROGENASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE;

CASE REPORT; CELL FUNCTION; CHEMOTAXIS; CHRONIC GRANULOMATOUS DISEASE; ENERGY METABOLISM; ENZYME ACTIVITY; ENZYME ASSAY; ERYTHROCYTE; GLUCOSE 6 PHOSPHATE DEHYDROGENASE DEFICIENCY; GRANULOCYTE; HUMAN; INFECTION RISK; LETTER; MALE; NEUTROPHIL; PRESCHOOL CHILD; PRIORITY JOURNAL; RESPIRATORY BURST;

ADULT; ANEMIA, HEMOLYTIC, CONGENITAL NONSPHEROCYTIC; CHEMOTAXIS, LEUKOCYTE; CHILD, PRESCHOOL; ERYTHROCYTES; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; GLUCOSEPHOSPHATE DEHYDROGENASE DEFICIENCY; GRANULOCYTES; HUMANS; IMMUNOLOGIC DEFICIENCY SYNDROMES; INFECTION; MALE; NEUTROPHILS; RESPIRATORY BURST; SPLENOMEGALY; TETRADECANOYLPHORBOL ACETATE;

EID: 0036168555     PISSN: 01928562     EISSN: None     Source Type: Journal    
DOI: 10.1097/00043426-200202000-00023     Document Type: Letter

References (10)

1. Nathan GN, Orkin SH. Nathan and Oski's hematology of infancy and childhood, 5th edn. Philadelphia: W.B. Saunders Co.; 1998.
2. Vives-Corrons JL, Feliu E, Pujades MA, et al. Severe glucose-6-phosphate dehydrogenase (G6PD) deficiency associated with chronic hemolytic anemia, granulocyte dysfunction, and increased susceptibility to infections: description of a new molecular variant (G6PD Barcelona). Blood 1982; 59:428-34.
3. Roos D, van Zwieten R, Wijnen JT, et al. Molecular basis and enzymatic properties of glucose-6-phosphate dehydrogenase volendam, leading to chronic nonspherocytic anemia, granulocyte disfunction, and increased susceptibility to infections. Blood 1999; 94:2955-62.
4. Mamlok RJ, Mamlok V, Mills GC, et al. Glucose-6-phosphate dehydrogenase deficiency, neutrophil dysfunction and Chromobacterium Violaceum sepsis. J Pediatr 1987; 111:852-4.
5. Gray GF, Klebanoff SJ, Stamatoyannopoulos G, et al. Neutrophil dysfunction, chronic granulomatous disease, and non-spherocytic anaemia caused by complete deficiency of glucose-6-phosphate dehydrogenase. Lancet 1973; 8:530-534.
6. Vulliamy TJ, Kaeda SK, Ait-Chafa D, et al. Clinical and haematological consequences of recurrent G6PD mutations and a single new mutation causing chronic nonspherocytic haemolytic anaemia. Br J Haematol 1998; 101:670-5.
7. WHO Scientific Group. Standarization procedures for the study of glucose-6-phosphate dehydrogenase. WHO Tech Rep Ser 1967:336.
8. Costa E, Cabeda JM, Vieira E, et al. Glucose-6-phosphate dehydrogenase aveiro: a de novo mutation associated with chronic nonspherocytic hemolytic anemia. Blood 2000; 95:1499-1501.
9. Coates TD, Beyer LL, Baehner RL. Laboratory evaluation of neutropenia and neutrophil dysfunction. In: Rose N, de Macano EC, Fahey JF, et al., eds. Manual of clinical laboratory immunology. Washington, DC: American Society for Microbiology, 1992:415-7.
10. Hirono A, Fuji H, Shima M, et al. G6PD Nara: A new class I glucose-6-phosphate dehydrogenase variant with an eight amino acid deletion. Blood 1993; 82:3250-2.