Resistance of succinic acid dimethyl ester insulinotropic action to exendin (9-39) amide

Hormone and Metabolic Research

Volumn 34, Issue 1, 2002, Pages 13-15

  Cancelas, J ^a   Garcia Martinez, J A ^a   Villanueva Penacarrillo M L ^a   Valverde, I ^a   Malaisse, W J ^b  

^a Hospital UniversitarioFundación Jiménez Díaz   (Spain)

^b FREE UNIVERSITY OF BRUSSELS   (Belgium)

Author keywords

Anaesthetized Rats; Exendin (9 39) Amid; Insulin Secretion; Succinic Acid Dimethyl Ester

Indexed keywords

AMIDE; EXENDIN [9-39] AMIDE; GLUCAGON LIKE PEPTIDE 1; SUCCINIC ACID DIMETHYL ESTER; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; DRUG RESISTANCE; GLUCOSE BLOOD LEVEL; HYPOGLYCEMIA; INSULIN LIKE ACTIVITY; INSULIN RELEASE; MALE; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALS; BLOOD GLUCOSE; INSULIN; MALE; PEPTIDE FRAGMENTS; RATS; RATS, WISTAR; SUCCINATES;

ANIMALIA;

EID: 0036167702     PISSN: 00185043     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2002-19960     Document Type: Article

References (8)

1. Suppression by exendin (9-39) amide of glucagon-like peptide 1 insulinotropic action in rats infused with dimethyl ester of succinic acid
2. Potentiation of glucagon-like peptide I insulinotropic action by succinic acid dimethyl ester
3. Potentiation of GLP-1 insulinotropic action by a non-glucidic nutrient in the pancreas of diabetic GK rats
4. Potentiation of the insulinotropic action of GLP-1 by succinic acid dimethyl ester in fed anaesthetised rats
5. Prolongation of the insulinotropic action of glucagonlike peptide 1 by the dimethyl ester of succinic acid in an animal model of type-2 diabetes
6. Glucose determination with glucose oxidase and peroxidase
7. Stimulation by D-glucose of protein biosynthesis in tumoral insulin-producing ceils (RINmSF line)
8. Respiratory, ionic and functional effects of succinate esters in pancreatic islets