Influence of t-PA and u-PA on adipose tissue development in a murine model of diet-induced obesity

Thrombosis and Haemostasis

Volumn 87, Issue 2, 2002, Pages 306-310

  Morange, P E ^a   Bastelica, D ^a   Bonzi, M F ^a   Van Hoef, B ^a   Collen, D ^a   Juhan Vague, I ^a   Lijnen, H R ^a  

^a UNIVERSITY OF LEUVEN   (Belgium)

Author keywords

Fibrinolysis; Mice; Obesity; t PA; u PA

Indexed keywords

TISSUE PLASMINOGEN ACTIVATOR; UROKINASE;

ADIPOSE TISSUE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD CLOTTING PARAMETERS; BODY WEIGHT; CELL COUNT; CELL SIZE; CELLULAR PARAMETERS; CONTROLLED STUDY; DISEASE MODEL; ENDOTHELIUM CELL; FAT INTAKE; MALE; METABOLIC PARAMETERS; MOUSE; NONHUMAN; OBESITY; PRIORITY JOURNAL; PROTEIN DEFICIENCY; STROMA CELL; SUBCUTANEOUS FAT; TISSUE GROWTH; WEIGHT GAIN;

EID: 0036166778     PISSN: 03406245     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-0037-1612990     Document Type: Article

References (18)

1. Development and disease in proteinase-deficient mice: Role of the plasminogen, matrix metalloproteinase and coagulation system
2. Absence of host plasminogen activator inhibitor 1 prevents cancer invasion and vascularization
3. Adipose tissue extracellular matrix: Newly organized by adipocytes during differentiation
4. Influence of PAI-1 on adipose tissue growth and metabolic parameters in a model of diet-induced obesity
5. Physiological consequences of loss of plasminogen activator gene function in mice
6. Guidelines for the use of animals in biomedical research
7. Microscopic fat cell size measurements on frozen-cut adipose tissue in comparison with automatic determinations of osmium-fixed fat cells
8. Effect of age, sex, and site on the cellularity of the adipose tissue in mice and rats rendered obese by a high fat diet
9. A simple method for the isolation and purification of total lipids from animal tissue
10. A procedure for measurements of distribution spaces in isolated fat cells
11. Immunoassay of murine t-PA, u-PA and PAI-1 using monoclonal antibodies raised in gene-inactivated mice
12. Function of the plasminogen/plasmin and matrix metalloproteinase systems in mice with targeted inactivation of fibrinolytic system genes
13. Molecular and cellular determinants of body weight regulation
14. Transgenic mouse models in angiogenesis and cardiovascular disease
15. The plasminogen activator inhibitor PAI-1 controls in vivo tumor vascularization by interaction with proteases, not vitronectin: Implications for angiogenic strategies
16. Leptin, the product of ob gene, promotes angiogenesis
17. Tissue distribution and regulation of plasminogen activator inhibitor-1 in obese mice
18. Clearance of tissue plasminogen activator (t-PA) and t-PA/plasminogen activator inhibitor type 1 (PAI-1) complex: Relationship to elevated tPA antigen in patients with high PAI-1 activity levels