Clonal expansion T cells identified in acute monoblastic leukemia by CDR3 size analysis of TCR Vβ repertoire using RT-PCR and genescan

Chinese Medical Journal

Volumn 115, Issue 1, 2002, Pages 69-71

  Li, Yangqiu ^a   Yang, Lijian ^a   Chen, Shaohua ^a   Li, Rongfu ^a   Zhang, Yuping ^a   Lu, Yuhong ^a   Luo, Gengxin ^a  

^a MEDICAL COLLEGE OF JINAN UNIVERSITY   (China)

Author keywords

AML M5; Genescan; T cell clonality; TCR V gene

Indexed keywords

LEUKEMIA ANTIGEN; T LYMPHOCYTE RECEPTOR BETA CHAIN;

ACUTE GRANULOCYTIC LEUKEMIA; ACUTE MONOCYTIC LEUKEMIA; ANTINEOPLASTIC ACTIVITY; ARTICLE; CELLULAR DISTRIBUTION; CLONAL VARIATION; CONTROLLED STUDY; GENE AMPLIFICATION; GENETIC ANALYSIS; GENETIC COMPLEMENTATION; HUMAN; HUMAN CELL; IMMUNE RESPONSE; LEUKEMIA CELL; PROTEIN EXPRESSION; PROTEIN FAMILY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; T LYMPHOCYTE; T LYMPHOCYTE RECEPTOR GENE;

COMPLEMENTARITY DETERMINING REGIONS; GENES, T-CELL RECEPTOR BETA; HUMANS; LEUKEMIA, MONOCYTIC, ACUTE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; T-LYMPHOCYTES;

EID: 0036166208     PISSN: 03666999     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (5)

1. Oligoclonality of tumor-infiltrating lymphocytes from human melanomas
2. Analysis of TCR usage in human tumors: A new tool for assessing tumor-specific immune response
3. High detection rate of T-cell receptor beta chain rearrangements in T-cell lymphoproliferations by family specific polymerase chain reaction in combination with the GeneScan technique and DNA sequencing
4. T cell clonality identification using genescan by CDR3 size of T cell receptor Vβ gene
5. T cell repertoire in patients with B chronic lymphocytic leukemia