Effect of aspirin on vasodilation to bradykinin and substance P in patients with heart failure treated with ACE inhibitor

British Journal of Clinical Pharmacology

Volumn 53, Issue 1, 2002, Pages 37-42

  Davie, Andrew P ^a   McMurray, John J V ^a  

^a WESTERN INFIRMARY   (United Kingdom)

Author keywords

ACE inhibitors; Aspirin; Bradykinin; Heart failure; Substance P

Indexed keywords

ACETYLSALICYLIC ACID; BRADYKININ; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; ENALAPRIL; SUBSTANCE P;

ADULT; AGED; ARTICLE; BLOOD FLOWMETRY; BLOOD PRESSURE; CLINICAL ARTICLE; CONFIDENCE INTERVAL; CONGESTIVE HEART FAILURE; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; FEMALE; FOREARM BLOOD FLOW; HUMAN; INFUSION; MALE; PRIORITY JOURNAL; PULSE RATE; VASODILATATION; VEIN OCCLUSION PLETHYSMOGRAPHY;

AGED; ANALYSIS OF VARIANCE; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; ASPIRIN; BRADYKININ; CONFIDENCE INTERVALS; CYCLOOXYGENASE INHIBITORS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG INTERACTIONS; FEMALE; HEART FAILURE, CONGESTIVE; HUMANS; MALE; MIDDLE AGED; SUBSTANCE P; VASODILATION;

EID: 0036164974     PISSN: 03065251     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.0306-5251.2001.01524.x     Document Type: Article

References (41)

1. Is aspirin safe for patients with heart failure?
2. Counteraction of the vasodilator effects of enalapril by aspirin in severe heart failure
3. Use of converting enzyme inhibitors in patients with asymptomatic left ventricular dysfunction
4. Inhibition of prostaglandin synthesis as a mechanism of action for aspirin-like drugs
5. Local inhibition of converting enzyme and vascular responses to angiotensin and bradykinin in the human forearm
6. Aspirin causes short-lived inhibition of bradykinin-stimulated prostacyclin production in man
7. Increased plasma level of substance P in patients with severe congestive heart failure treated with ACE inhibitors
8. Endothelium-dependent contraction in intrapulmonary arteries. Mediation by endothelial NK1 receptors and TXA2
9. Even low dose aspirin impairs arachidonic acid-induced vasodilatation in heart failure
10. Measuring forearm blood flow and interpreting the responses to drugs and mediators
11. How reproducible is bilateral forearm plethysmography?
12. Bradykinin as a vasodilator in man
13. Impaired endothelium-dependent vasodilation in patients with essential hypertension. Evidence that nitric oxide abnormality is not localized to a single signal transduction pathway
14. Role of bradykinin in the vasodilator effects of losartan and enalapril in patients with heart failure
15. Effect of angiotensin-(1-7) and bradykinin in patients with heart failure treated with an ACE inhibitor
16. Comparison of angiotensin-converting enzyme inhibition with angiotensin II receptor antagonism in the human forearm
17. Endothelium- dependent forearm vasodilation to acetylcholine but not to substance P is impaired in patients with heart failure
18. Endothelial control of lower limb blood flow in chronic heart failure
19. The influence of atherosclerosis on the mechanical responses of isolated human coronary arteries to substance P, isoprenaline and noradrenaline
20. Plasma exudation in conscious dogs with experimental heart failure
21. Continuous release of vasodilator prostanoids contributes to regulation of resting forearm blood flow in humans
22. The effect of aspirin on pain and hand blood flow responses to intra-arterial injection of bzadykinin in man
23. Inhibition of prostaglandin biosynthesis as the mechanism of analgesia of aspirin-like drugs in the dog knee joint
24. Relaxant effect of aspirin-like drugs on isolated guinea pig tracheal chain
25. Prostaglandins and the contractile action of bradykinin on the longitudinal muscle of rat isolated ileum
26. Differential effect of aspirin on thromboxane and prostaglandin biosynthesis in man
27. Suppression of thromboxane A2 but not of systemic prostacyclin by controlled-release aspirin
28. Transdermal modification ofplatelet function: A dermal aspidm preparation selectively inhibits platelet cyclooxygenase and preserves prostacyclin biosynthesis
29. Vasodilatation to arachidonic acid in humans. An insight into endogenous prostanoids and the effects of aspirin
30. Actions of bradykinin on isolated cerebral and preipheral arteries
31. Bradykinin-induced vasoconstriction of rat mesenteric arteries preconstricted with noradrenaline
32. Inhibition by nicotine of the vasodilator effect of bradykinin: Evidence for a prostcyclin-dependent mechanism
33. Endothelial and non-endothelial cyclooxygenase mediate rabbit pial arteriole dilation by bradykinin
34. Acute ACE inhibition causes plasma extravasation in mice that is mediated by bradykinin and substance P
35. Resolution of ACE inhibitor cough: Changes in subjective cough and responses to inhaled capsaicin, intradermal bzadykinin and substance-P
36. The effect of local converting enzyme inhibition on the dilator response to substance P in the human forearm
37. Acetylsalicylic acid, paracetamol and morphine inhibit behavioral responses to intrathecally administered substance P or capsaicin
38. Substance P in human hand veins in vivo, tolerance, efficacy, potency, and mechanism of venodilator action
39. Aspirin improves endothelial dysfunction in atherosclerosis
40. Congestive heart failure, involvement of perivascular peptides reflecting activity in sympathetic, parasympathetic and afferent fibres
41. Angiotensin-(1-7) a new hormone of the angiotensin system