Chelation in metal intoxication: Influence of cysteine or N-acetyl cysteine on the efficacy of 2,3-dimercaptopropane-1-sulphonate in the treatment of cadmium toxicity

Journal of Applied Toxicology

Volumn 22, Issue 1, 2002, Pages 67-71

  Tandon, Sushil K ^a   Prasad, Satgur ^a   Singh, Surendra ^a  

^a CSIR INDIAN INSTITUTE OF TOXICOLOGY RESEARCH   (India)

Author keywords

Cadmium; Chelation; Cysteine; DMPS; Metallothionein; N acetyl cysteine; Rat

Indexed keywords

ACETYLCYSTEINE; CADMIUM; COPPER; CYSTEINE; METALLOTHIONEIN; UNITHIOL; ZINC;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD LEVEL; CADMIUM POISONING; CELL FRACTIONATION; CELL NUCLEUS; CHELATION; CONTROLLED STUDY; COPPER BLOOD LEVEL; CYTOSOLIC FRACTION; DRUG EFFICACY; FEMALE; LIVER LEVEL; MITOCHONDRION; NONHUMAN; PRIORITY JOURNAL; RAT; SUPERNATANT; TISSUE DISTRIBUTION; ZINC BLOOD LEVEL;

ACETYLCYSTEINE; ANIMALS; CADMIUM; CHELATING AGENTS; CYSTEINE; DRUG INTERACTIONS; FEMALE; KIDNEY; LIVER; METALLOTHIONEIN; RATS; TREATMENT OUTCOME; UNITHIOL;

ANIMALIA;

EID: 0036159222     PISSN: 0260437X     EISSN: None     Source Type: Journal    
DOI: 10.1002/jat.827     Document Type: Article

References (15)

1. 2,3-Dimercapto-1-propane sulfonate in heavy metal poisoning
2. Mobilization of heavy metals by newer, therapeutically useful chelating agents
3. Role of chelating agents for prevention, intervention and treatment of exposures to toxic metals
4. 3DTPA and DMPS in the rat
5. Renal glutathione depletion and nephrotoxicity of cadmium-metallothionein in rats
6. Chelation in metal intoxication XXXI: Influence of methionine supplementation in chelation of lead in rat
7. Influence of methionine and zinc supplementation during chelation of lead in rats
8. Time related influence of α-mercapto-β-(2-furyl) acrylic acid (MFA) in cadmium toxicity
9. Efficacy of amphipathic dithiocarbamates in intracellular cadmium mobilization and in modulation of hepatic and renal metallothionein in cadmium pre-exposed rat
10. Comparison of metallothionein determination by polarographic and cadmium-saturation methods
11. Detecting the effects of cadmium toxicity
12. The protocol for the safe and effective administration of EDTA and other chelating agents for vascular disease, degenerative disease and mental toxicity
13. Effect of cadmium mobilizing dithiocarbamates on essential trace metal metabolism in rats
14. Chelation in metal intoxication XLI: Efficacy of amphipathic dithiocarbamates in mobilization of lead in the rat