Effect of mitomycin-C on the bioavailability of the radiopharmaceutical 99mTechnetium-Phytic acid in mice: A model to evaluate the toxicological effect of a chemical drug

Journal of Applied Toxicology

Volumn 22, Issue 1, 2002, Pages 85-87

  Gomes, Maria Luisa ^a   De Braga, Ana Cristina Souza ^a   De Mattos, Deise Mara Machado ^a   De Freitas, Rosimeire Souza ^a   De Paula, Emílio Faustino ^b   Bezerra, Roberto José A C ^b   Bernardo Filho, Mario ^c  

^a STATE UNIVERSITY OF RIO DE JANEIRO   (Brazil)

^b FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

^c INSTITUTO NACIONAL DE CÂNCER   (Brazil)

Author keywords

99mTc PHY; Chemotherapeutic drug; Drug interaction; Mitomycin C

Indexed keywords

ANTINEOPLASTIC AGENT; MITOMYCIN C; PHYTIC ACID; RADIOPHARMACEUTICAL AGENT; TECHNETIUM 99M;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE; BRAIN; CALCULATION; CELL STRUCTURE; CONTROLLED STUDY; DOSE RESPONSE; DRUG BIOAVAILABILITY; DRUG DISTRIBUTION; DRUG POTENTIATION; HEART; ISOTOPE LABELING; KIDNEY; LIVER; LIVER SCINTISCANNING; LUNG; MOUSE; NONHUMAN; OVARY; PANCREAS; PANCREAS ADENOCARCINOMA; PRIORITY JOURNAL; RADIOACTIVITY; SPLEEN; STOMACH; STOMACH ADENOCARCINOMA; STREPTOMYCES; THYMUS; THYROID GLAND; UTERUS;

ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; BIOLOGICAL AVAILABILITY; FEMALE; MICE; MICE, INBRED BALB C; MITOMYCIN; MODELS, ANIMAL; ORGANOTECHNETIUM COMPOUNDS; PHYTIC ACID; RADIOPHARMACEUTICALS; TISSUE DISTRIBUTION;

ANIMALIA; STREPTOMYCES;

EID: 0036159008     PISSN: 0260437X     EISSN: None     Source Type: Journal    
DOI: 10.1002/jat.798     Document Type: Article

References (24)

1. Essentials of Nuclear Medicine Science
2. Fundamentals of Nuclear Pharmacy
3. 99mtechnetium
4. Labeling of red blood cells with 99 m technetium: A very simple kit
5. 99mTc-pertechnetate binding by human serum and tissues
6. Drug-induced changes in the biologic distribution of radiopharmaceuticals
7. Model to evaluate the biological effect of natural products: Vincristine action on the biodistribution of radiopharmaceuticals in Balb/c female mice
8. Radiopharmaceutical-related pitfalls and artifacts
9. Drug interactions with radiopharmaceuticals
10. 99mTc-labelled glucoheptonic acid in Balb/c mice
11. Adverse reactions and drug interactions with radiopharmaceuticals
12. Textbook of Radiopharmacy - Theory and Practice
13. Non enzymatic and enzymatic activation of mitomycin-C: Identification of a unique cytosolic activity
14. Cytotoxic potential of monoalkylation products between mitomycins and DNA: Studies of decarbamoyl mitomycin-C in wild-type and repair deficient cell lines
15. 99mTc-MDP) to blood elements Braz
16. Effect of the tobacco on the labeling of red blood cells and plasma proteins with technetium-99m
17. Gallium-67/stable gadolinium antagonism: MRI contrast markedly alters the normal biodistribution of gallium-67
18. Mitomycin-C effect on the biodistribution of the radiopharmaceutical technetium-99m-methylenediphosphonic acid in Balb/c mice
19. Drugs used in cancer chemotherapy
20. 99mTc-DTPA in Balb/c female mice