Synergistic cytotoxic effect between serine-threonine phosphatase inhibitors and 5-fluorouracil: A novel concept for modulation of cytotoxic effect

Cancer Chemotherapy and Pharmacology

Volumn 49, Issue 2, 2002, Pages 111-118

  Islam, Md ^a,b,c   Begum, Salma ^a,b,c   Lin, Ling ^a,b,c   Okamura, Atsushi ^a,b,c   Du, Ming ^a,b,c   Fujimura, Shinji ^a,b,c  

^a CHIBA UNIVERSITY   (Japan)

^b UNIVERSITY OF TORONTO   (Canada)

^c University of Alabama at Birmingham   (United States)

Author keywords

5 Fluorouracil; Cytotoxicity; Microcystin LR; Phosphatase inhibitors; Synergism; Thymidine kinase

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; CALICULIN A; CYANOGINOSIN LR; DNA; FLUOROURACIL; OKADAIC ACID; PHOSPHOPROTEIN PHOSPHATASE INHIBITOR; RNA; TETRAZOLIUM; THYMIDINE KINASE; THYMIDYLATE SYNTHASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; ASSAY; CANCER INHIBITION; CELL PROLIFERATION; CLONOGENIC ASSAY; COLON ADENOCARCINOMA; CONCENTRATION RESPONSE; CONTROLLED STUDY; CULTURE MEDIUM; DRUG CYTOTOXICITY; DRUG DNA INTERACTION; DRUG EFFECT; DRUG POTENTIATION; ENZYME ACTIVITY; ENZYME INACTIVATION; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; IN VITRO STUDY; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SARCOMA; STOMACH CARCINOMA; UTERINE CERVIX CARCINOMA;

ANIMALS; ANTINEOPLASTIC AGENTS; DRUG SYNERGISM; ENZYME INHIBITORS; FLUOROURACIL; MALE; MICE; MICE, INBRED ICR; MICROCYSTINS; OKADAIC ACID; PEPTIDES, CYCLIC; PHOSPHOPROTEIN PHOSPHATASE; PHOSPHORYLATION; THYMIDINE KINASE; TUMOR CELLS, CULTURED;

EID: 0036158753     PISSN: 03445704     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00280-001-0397-z     Document Type: Article

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