Radiochemical synthesis and biodistribution of a novel maxi-K potassium channel opener

Nuclear Medicine and Biology

Volumn 29, Issue 1, 2002, Pages 55-59

  Kiesewetter, Dale O ^a   Jagoda, Elaine M ^a   Starrett Jr, John E ^b   Gribkoff, Valentin K ^b   Hewawasam, Piyasena ^b   Srinivas, Nugahally ^b   Salazar, Daniel ^b   Eckelman, William C ^a  

^a NATIONAL INSTITUTES OF HEALTH   (United States)

^b BRISTOL MYERS SQUIBB PHARMACEUTICAL RESEARCH INSTITUTE   (United States)

Author keywords

Biodistribution; BMS 204352; Brain; Maxi K; MaxiPost; PET

Indexed keywords

(5 CHLORO 2 METHOXYPHENYL) 1,3 DIHYDRO 3 FLUORO 6 (TRIFLUOROMETHYL) 2H INDOL 2 ONE F 18; 3 (5 CHLORO 2 METHOXYPHENYL) 3 FLUORO 2,3 DIHYDRO 6 TRIFLUOROMETHYL 1H INDOL 2 ONE; CALCIUM; FLUORINE 18; POTASSIUM CHANNEL; POTASSIUM CHANNEL STIMULATING AGENT; SILVER; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BINDING ASSAY; BRAIN; CONTROLLED STUDY; DRUG ACCUMULATION; DRUG DISTRIBUTION; DRUG MECHANISM; DRUG SPECIFICITY; DRUG SYNTHESIS; DRUG UPTAKE; ENANTIOMER; ISOTOPE LABELING; NONHUMAN; RADIOCHEMISTRY; RAT; TISSUE DISTRIBUTION;

ANIMALS; BRAIN; INDOLES; NEUROPROTECTIVE AGENTS; POTASSIUM CHANNELS; RATS; TISSUE DISTRIBUTION;

EID: 0036153730     PISSN: 09698051     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0969-8051(01)00281-5     Document Type: Article

References (9)

1. Differential expression of the a and b subunits of large-conductance calcium-activated potassium channel: Implication for channel diversity
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