Molecular cloning and analysis of the Cryptosporidium parvum aminopeptidase N gene

International Journal for Parasitology

Volumn 32, Issue 2, 2002, Pages 187-197

  Padda, Ranjit S ^a   Tsai, An ^a   Chappell, Cynthia L ^a,b   Okhuysen, Pablo C ^a,b  

^a UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF TEXAS SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

Aminopeptidase N; Cryptosporidium; Protease

Indexed keywords

AMINOPEPTIDASE; ARGINYLGLYCYLASPARTIC ACID; MESSENGER RNA;

PARASITOLOGY;

AMINO ACID SEQUENCE; ARTICLE; ARTIFICIAL CHROMOSOME; CELL ADHESION; CELL LINE; CONTROLLED STUDY; CRYPTOSPORIDIUM PARVUM; EUKARYOTE; GENE EXPRESSION; GENE PROBE; GENETIC ANALYSIS; GENETIC CONSERVATION; GENOME; INTESTINE CELL; MOLECULAR CLONING; NONHUMAN; PROKARYOTE; PROTEIN MOTIF; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEQUENCE ANALYSIS; SEQUENCE HOMOLOGY; SPOROZOITE;

AMINO ACID SEQUENCE; ANIMALS; ANTIGENS, CD13; BASE SEQUENCE; BLOTTING, SOUTHERN; CELLS, CULTURED; CLONING, MOLECULAR; CRYPTOSPORIDIUM PARVUM; DNA, PROTOZOAN; GENE LIBRARY; HUMANS; MOLECULAR SEQUENCE DATA; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SEQUENCE HOMOLOGY, AMINO ACID;

CRYPTOSPORIDIUM; CRYPTOSPORIDIUM PARVUM; EUKARYOTA; PROKARYOTA;

EID: 0036153721     PISSN: 00207519     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0020-7519(01)00317-4     Document Type: Article

References (35)

1. Protein database searches for multiple alignments
2. Improved purification methods for calf-derived Cryptosporidium parvum oocysts using discontinuous sucrose and cesium chloride gradients
3. Toxoplasma gondii: Purification and characterization of an immunogenic metallopeptidase
4. Establishing the Cryptosporidium parvum karyotype by NotI and SfiI restriction analysis and Southern hybridization
5. Molecular cloning and expression of a gene encoding Cryptosporidium parvum glycoproteins gp40 and gp15
6. Codon usage in Cryptosporidium parvum differs from that in other Eimeriorina
7. Aminopeptidases from Plasmodium falciparum, Plasmodium chabaudi chabaudi and Plasmodium berghei
8. The infectivity of Cryptosporidium parvum in healthy volunteers
9. A Plasmodium falciparum aminopeptidase gene belonging to the M1 family of zinc-metallopeptidases is expressed in erythrocytic stages
10. Protease activity associated with excystation of Cryptosporidium parvum oocysts
11. Antagonistic effect of human alpha-1-antitrypsin on excystation of Cryptosporidium parvum oocysts
12. Synergistic anticryptosporidial potential of the combination alpha-1-antitrypsin and paromomycin
13. The role of aminopeptidases in haemoglobin degradation in Plasmodium falciparum-infected erythrocytes
14. Complete development and long term maintenance of Cryptosporidium parvum human and cattle genotypes in cell culture
15. Cryptosporidiosis. A global challenge
16. Plasmodium chabaudi chabaudi and P. falciparum: Inhibition of aminopeptidase and parasite growth by bestatin and nitrobestatin
17. A metallo-dependent cysteine proteinase of Cryptosporidium parvum associated with the surface of sporozoites
18. The complete amino acid sequence of human muscle glyceraldehyde 3-phosphate dehydrogenase
19. Arginine aminopeptidase, an integral membrane protein of the Cryptosporidium parvum sporozoite
20. Cryptosporidium parvum metalloaminopeptidase inhibitors prevent in vitro excystation
21. Some aspects of protozoan parasite-host cell interactions with special reference to RGD-mediated recognition process
22. Protein modeling by e-mail
23. ProMod and Swiss-Model: Internet-based tools for automated comparative protein modelling
24. Construction and characterisation of a genomic PAC library of the intestinal parasite Cryptosporidium parvum
25. Cysteine proteinases and the pathogenesis of amebiasis
26. Evolutionary families of peptidases
27. The major surface protein of Leishmania promastigotes is a fibronectin-like molecule
28. A highly conserved amino-acid sequence in thrombospondin, properdin and in proteins from sporozoites and blood stages of a human malaria parasite
29. Proteases of malaria parasites: New targets for chemotherapy
30. Characterization of native and recombinant falcipain-2, a principal trophozoite cysteine protease and essential hemoglobinase of Plasmodium falciparum
31. Cysteine protease secreted by Paragonimus westermani attenuates effector functions of human eosinophils stimulated with immunoglobulin G
32. Preliminary profile of the Cryptosporidium parvum genome: An expressed sequence tag and genome survey sequence analysis
33. Cloning and sequence analysis of a highly polymorphic Cryptosporidium parvum gene encoding a 60-kilodalton glycoprotein and characterization of its 15- and 45-kilodalton zoite surface antigen products
34. CLUSTAL W: Improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice
35. A tyrosine residue essential for catalytic activity in aminopeptidase A